Compressibility parameter

Subsequent to these successful pilot scale trials, the formulation was scaled-up to the production launch site. Once again, only those parameters recognized as critical were modified during manufacture. The compression parameters that were modified were speed and hardness. A total of four production-sized batches were manufactured, with the first batch being compressed on a 43 station Fette 2080 rotary tablet press, and three subsequent batches compressed on a 36 station Fette 2090 rotary tablet press. Three compression speeds and three compression forces were successfully evaluated... 

Powder compressibility parameter k [M I,T- = AWCAp-V,) (where AV and Ap are the changes in tablet volume V and applied pressure p, respectively, and Vf is the final tablet volume)... 

For the purpose of this study, the average powder compressibility parameter K was calculated as shown in Table 6. 

The standard hydrates of si, sll, and sH were assumed to be the empty hydrates of methane, propane, and methane + neohexane, respectively. While the thermal expansion parameters are the same for the real and standard hydrates, the compressibility parameter and standard volume are not. The volumetric compressibilty of the standard hydrates of si, sll, and sH are 3E-5,3E-6, and 3E-7,... 

Regressed Linear Compressibility Parameters for Hydrate Volume (Multiply by 3 to Get Volumetric Compressibility Parameters)... 

The choice of optimum compression parameters to maximize speech intelligibility or speech quality is still open to contention. Rapid attack time constants (less than 5 ms) are accepted in the industry and also by researchers to prevent transients from saturating the output power amplifier. Arguments for fast release times (less than 20 ms), also termed syllabic compression, are based on considerations of the syllabic variations in speech and the desire to amplify soft speech sounds on a nearly instantaneous basis... 

Moreover, the bread crumb s moisture loss during seven days of storage open to the air, also did not show a consistent dramatic effect on these two tensile parameters (Chen et al. 1994) as one would expect. The same can be said about the compression parameters, which too showed little correlation with the moisture loss, which was measurable, of course. These reported findings, if indeed representative of the three tested breads (white, Canadian and whole wheat), would suggest that the initial textural changes that accompany bread staling are quite subtle and hence cannot be always manifested in the described crude mechanical parameters. An alternative explanation is that the failure to find the expected trends was mainly due to the large scatter in the experimental results that masked the true trend, if it really existed. 

Alderbom G. A novel approach to derive a compression parameter indicating effective particle deformability. Pharm Dev Technol 2003 8 367-377. 

The first simplification was suggested by Olabisi and Simha [1977]. Combining Tail s equation (6.10) with the volume-temperature dependence of the S-S equation of state, Eq. (6.23), and the linear dependence observed for the Tail compressibility parameter, — In B = 0.04615 + 49.22T, the authors wrote... 

The shape of compression parameter as presented in Figure 62.11 is a result of two phenomena, which superimpose... 

Strength and compressibility parameters may be assessed from triaxial and consolidation tests results carried out on extruded samples that have been reconstituted to specified compaction requirements i.e. proctor test requirements. Collapsed type settlement may be estimated by repeating the consolidation test on saturated samples for each load increment. 

To overcome this computational dilemma, Constans et al. created an efficient algorithm that proceeds in different steps. Using the ASA method, the authors succeed in replacing the true integral measure of Eq. [21] by a summation, which was accomplished by introducing a function in the ASA density expression that effectively compresses the atomic shells. In the limit, the atomic electron densities are infinitely compacted into the nuclei. To illustrate the procedure, consider first expression [42]. A compression parameter 1 is introduced in the different shells such that... 

Based on the above discussion, it is expected that the refractive index of a sample varies with temperature, pressure, and its composition. The decrease in refractive index with increasing temperature and decreasing pressme is primarily the result of the expansion of the media volume and decrease in density, causing the light beam to encovmter fewer molecules per unit distance. These effects can be calculated by considering thermal expansion or compressibility parameters. 

Desgreniers S (1998) High-density phases of ZnO structural and compressive parameters. Phys RevB58 14102-1405... 

Here, each component species is specified by index a the first term of the integrand describes the repulsion between a and a beads, whose strength is controlled by the Flory-Huggins parameter/ the second term gives the system a compressibility, which is controlled by the compressibility parameter k. In the framework of the MFA, the coiresponding mean-field density-dependent potential can be written as follows " ... 

Thermal parameters affecting the crystallization of sorbitol have been studied depending on conditions, two crystalline modifications can arise, and a process for the rapid crystallization of molten sorbitol was proposed. Compression parameters of crystalline xylitol have also been reported. The viscosity of concentrated aqueous solutions of sodium and potassium halides in presence of D-mannitol has been studied the viscosity was related to the structure-making or structure-breaking effect of the salt in solution. ... 

---