Composition congeneric

People are environmentally exposed to PBBs and PBDEs of different congeneric composition than the source commercial mixtures, due to differential partitioning and transformation of the individual congeners in the environment, including transformation in food animals (e.g., dairy cattle in the case of PBBs). Additionally, as discussed in Section 3.4, because PBBs and PBDEs are lipophilic and some congeners are not readily metabolized, they are likely to be retained in the body for long periods of time (years). 

People are environmentally exposed to PBB and PBDE mixtures of different congeneric composition than the original commercial PBB and PBDE mixtures. Although the toxicity or potency of environmental PBB and PBDE mixtures consequently may be greater or less than that of commercial mixtures, there are insufficient mixture toxicity data on which to directly base MRLs for environmental PBBs and PBDEs. 

As previously mentioned, neurobehavioral alterations have been observed in rats and monkeys following pre- and/or postnatal exposure to conunercial Aroclor mixtures, defined experimental congener mixtures, single PCB congeners, and Great Lakes contaminated fish. Monkeys exposed from birth to age 20 weeks to PCB mixtures of congeneric composition and concentration similar to that found in human breast milk... 

The synthetic manifold in Scheme 5.9 summarizes the preparation of mixed-core [Fe4(N Bu) S4 Cl4P cubane clusters [n = 1-3 35-37). The homoleptic [n, z] = [0,2-/3-] and [4,0/1-] parent species are established, fundamental clusters in Fe-S and Fe-NR chemistry, and the mixed-core derivatives complete the congeneric set. The individual core-heteroligated clusters were synthesized via specific, composition-selective routes, with pure products isolated in moderate-to-good yields. The final cubane assembly reactions are all formal fragment condensations that employ a range of di- and... 

This chapter has clearly shown molecular quantum similarity to be a worthy field of research with a large range of appHcations. It allows quantification of the similarity between any pair of atoms or molecules, and it can be used by chemists for all quantum entities for which a density probability function is available. Consequently, molecular similarity can be extended far beyond the traditional approaches that address mainly congeneric molecules, or molecules differing in substituent composition. 

Step 4 Oil Composition by Congeneric Group, Resulting Intake... 

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