Cognitive function and

Mohler H (2007) Molecular regulation of cognitive functions and developmental plasticity impact of GABAa receptors. Neurochem 102 1-12... 

Another theory for the action of stimulant diugs in ADHD involves effects on nonstiiatal monoamine systems. Frontal cortical dopamine, norepinephrine, and serotonin are clearly important in cognitive functioning and impulse control. These neurotransmitters directly modulate reward-related behaviors associated with the striatal dopamine system. Moreover, the amygdala may be pharmacologically influenced leading to enhanced... 

Gottschalk C, Beauvais J, Hart R, et al Cognitive function and cerebral perfusion during cocaine abstinence. Am J Psychiatry 158 540-545, 2001... 

Generally, anticholinesterases produce some improvement in cognitive function and the quality of life in the early stages of AzD but that needs to be balanced against side-effects. 

In summary, HRT improves overall well-being and mood in women with vasomotor symptoms, but it has not demonstrated an improvement in QOL in women without vasomotor symptoms, does not improve cognitive function, and has little effect, if any, on QOL measures. 

Alzheimer s disease A progressive neurodegenerative disorder and the most common type of senile dementia. It is characterised by a marked decline in cognitive functioning and severe behavioural disturbances. 

Wood RH, Reyes-Alvarez R, Maral B, Metoyer KL and Welsch MA (1999). Physical fitness, cognitive function, and health-related quality of life in older adults. Journal of Aging and Physical Activity, 1, 217-230. 

Yamamoto, K. Analysis of cognitive function and regional cerebral blood flow in Parkinson s disease by 123I-IMP SPECT. Rinsho Shinkeigaku 32 1-7,1992. 

With the recognition that SERMs have differential tissue-dependent effects on ER function, there has been recent interest in the effects of raloxifene, tamoxifen, and other SERMs on mood, sleep, cognitive function, and AD severity. What follows is an analysis of the effects of SERMs on several conditions. 

Palomba et al. (2004) have also studied the effects on cognigtion, mood, and QoL in 100 premenopausal women with symptomatic uterine leiomyomas treated with gonadotropin-releasing hormone agonist with or without raloxifene. The findings demonstrate that raloxifene is not able to prevent decreases in cognitive function and does not reduce the depresion and anxiety symptoms in women treated with GnRHa. 

Nickelsen T, Lufkin EG, Riggs BL, Cox DA, Crook TH (1999) Raloxifene hydrochloride, a selective estrogen receptor modulator safety assessment of effects on cognitive function and mood in postmenopausal women. Psychoneuroendocrinology 24 115-128... 

Araki, S. (1992). Auditory event-related potential (P300) in relation to peripheral nerve conduction in workers exposed to lead, zinc, and copper Effects of lead on cognitive function and central nervous system. Amer. J. bid. M (Ed.), 21(4) 39-547. 

Official Title Effect of EGb 761 on the Ratio of the Isoforms of the Protein Precursor of Beta Amyloid Platelets on Patients With Mild to Moderate Alzheimer s Disease. A Phase II, Randomized, Double-Blind Trial, on Parallel Groups Versus Placebo Primary Outcome Measures Effect of EGb 761 on the ratio of the isoform of the protein precursor of beta amyloid platelets Secondary Outcome Measures Efficacy of EGb 761 on the cognitive functions and safety of EGb 761 at a dosage of 240 mg per day Total Enrollment 40 Study Start July 2005... 

Dementia is a general term for loss of cognitive functions and behavioral impairment. It may arise from several etiologies and may present with a large variety of manifestations. The financial cost in health care engendered by dementia is enormous, because individuals with dementia require progressive amounts of supervision, eventually needing total care. The human and emotional costs are unquantifiable. Several forms of dementia exist, which will be briefly classified and described here. 

Winther K, Randlov C, Rein E, Mehlsen J. (1998). Effects of Ginkgo biloba extract on cognitive function and blood pressure in elderly subjects. Curr Therapeutic Res. 59(12) 881-88. 

Gitelman DR, Prohovnik I. (1992). Muscarinic and nicotinic contributions to cognitive function and cortical blood flow. Neurobiol Aging. 13(2) 313-18. 

Peters BA, Lewis EG, Dustman RE, Straight RC, Beck EC. (1976). Sensory, perceptual, motor, and cognitive functioning and subjective reports following oral administration of delta9-tetrahydrocannabinol. Psychopharmacologia. 47(2) 141-48. 

To understand whether cognitive function and mood disorders are cooperatively influenced by genetic factors in AD and to know the potential impact that conventional neuroprotection can exert on mood disorders, we studied the effect of the therapeutic CNLA protocol on anxiety in AD and the differential APOE- and ACE-related responses distinguishing the influence of monogenic and bigenic variants on emotional conditions. 

Das U. (2008) Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer s disease — but how and why PLEFA 78 11-19. 

Although limited by dose-response information, impairment of both neurophysiological and psychological functions (including slowing of reaction time, balance dysfunction, reductions in cognitive function, and deficits of recall) has been associated with chronic chlordane exposure. ... 

Huntington disease is an autosomal dominant disorder involving degeneration of the striatum and cortex that manifests as motor dysfunction in midlife and leads to progressive loss of cognitive function and death. 

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