Cetomacrogol emulsifying wax

Cetomacrogol emulsifying wax BP [20] - non-ionic, containing 20 % of macrogol cetostearyl ether, a strong o/w emulsifier and 80 % cetostearyl alcohol, a weak w/o emulsifier... 

The selection of the surfactant is mainly based on the compatibility with the active substance. Sodium lauryl sulfate is an anionic surfactant and therefore incompatible with cationic active substances. Cetomacrogol emulsifying wax BP is incompatible with high concentrations of phenolic substances due to an interaction of the phenolic group with the polyethylene glycol chains in the macrogol cetostearyl ether. It is compatible with acids, high concentrations of electrolytes and cations. 

The lipophilic base is formulated in the same way as hydro-phobic ointments, see Sect. 12.5.2. The o/w emulsifiers are usually the same as in o/w creams for example cetomacrogol emulsifying wax and lanette emulsifying wax (lanette wax SX or N). As these bases are anhydrous... 

Cetomacrogol emulsifying wax (BP) 15 g. Sorbic acid 200 mg, Decyl oleate 20 g, Sorbitol, liquid (crystallising) 4 g. Water, purified 60,8 g. Total 100 g... 

The name includes the average molecular mass of the chain length 1,000 (corresponding with approximately 20 glycol units). Cetomacrogol emulsifying wax is an emulsifier (see Sect. 18.4.3) and consists for 80 % of cetostearyl alcohol and 20 % from cetomacrogol 1000. The substance is incompatible with phenolic compounds (phenol, resorcinol) but low concentrations may be tolerated (see Sect. 12.5.7). 

Cetomacrogol 1(XX) B.P.C. is a water-soluble compound with an alkyl chain length of 15 or 17 and an oxyethylene chain length of between 20 and 24. It is used in the form of cetomacrogol emulsifying wax in the preparation of oil-in-water emulsions and also as a solubilizing agent for volatile oils. 

Wax BP, Cetomacrogol Emulsifying Wax BP and Cetrimide Emulsifying Wax (BP) are ready prepared mixtures for extemporaneous use. When these or similar mixtures are used the resultant emulsions are mobile at low emulsifier concentrations and semi-solid at moderate concentrations (about 10% or less of the total weight of the emulsion). The process whereby the surfactant mixture imparts the semi-solid characteristics over a period of time has been termed self-bodying [92-94], the essential feature of which is the introduction of a significant elastic... 

Uses Emulsifier, SE base for cosmetic/pharmaceulical o/w emulsions, creams, lotions, esp. suitable for processing cationics Regulatory BP compliance for Cetomacrogol emulsifying wax Properties Wh. flakes, faint char, odor solid, pt. 48-53 C add no. 0.5 max. sapon. 

Nonionic emulsifying wax is also used in nonaqueous ointment bases, such as cetomacrogol emulsifying ointment BP, and in barrier creams. 

Uses Cetomacrogol self-emulsifying wax emulsifier and thickener for cosmetic emulsions... 

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