Macrogol cetostearyl ether

The polyoxyethylene alkyl ethers are a series of polyoxyethylene glycol ethers of n-alcohols (lauryl, oleyl, myristyl, cetyl, and stearyl alcohol). Of the large number of different materials commercially available, four types are listed in the USPNF 23, one type in the JP 2001, and four types in the PhEur 2005. BP Macrogol cetostearyl ether... [Pg.564]

Cetomacrogol emulsifying wax BP [20] - non-ionic, containing 20 % of macrogol cetostearyl ether, a strong o/w emulsifier and 80 % cetostearyl alcohol, a weak w/o emulsifier... [Pg.243]

The selection of the surfactant is mainly based on the compatibility with the active substance. Sodium lauryl sulfate is an anionic surfactant and therefore incompatible with cationic active substances. Cetomacrogol emulsifying wax BP is incompatible with high concentrations of phenolic substances due to an interaction of the phenolic group with the polyethylene glycol chains in the macrogol cetostearyl ether. It is compatible with acids, high concentrations of electrolytes and cations. [Pg.243]

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