Central nervous system tumors

Patients with seizure disorders should not take bupropion. Similarly, an alternative treatment should be considered in the case of patients with a history of significant head trauma, a central nervous system tumor, or an active eating disorder. 

Stebbings JH, Semkiw W. 1989. Central nervous system tumors and related intracranial pathologies in radium dial workers. Br J Radiol 21 63-66. 

Fontanesi, J., Heideman, R.L., Muhlbauer, M., Mulhem, R., Sanford, R.A., Douglass, E.C., Kovnar, E., Ochs, J.J., Kuttesch, J.F., Tai, D. et al. (1995). High-activity interstitial irradiation in the treatment of pediatric central nervous system tumors a pilot study. Pediatr. Neurosurg. 22 289-97. 

Obesity is a condition that is influenced by genetic and environmental factors (such as energy intake and expenditure, fetal nutrition, culture). There are four major physiological causes of obesity endocrine disorders (growth hormone deficiency, Cushing syndrome), genetic syndromes (Prader-Willi syndrome or Alstrom syndrome), disorders of the central nervous system (tumor, trauma) or the most common cause, multifactorial or primary obesity (caused by an interaction of multiple genes). 

In another study children aged 0-14 years with leukemia (n — 150), lymphomas (n = 46), central nervous system tumors (n — 79), a range of other solid tumours (n = 142), and a subset of acute lymphoblastic leukemia (n = 129) were compared with 111 children matched for age and sex (30). Odds ratios showed no significant positive association for leukemias (1.30 0.83, 2.03), acute lymphoblastic leukemia (1.21 0.74, 1.97), lymphomas (1.06 0.46, 2.42), central nervous system tumors (0.74 0.40, 1.34), and other solid tumors (0.59 0.37, 0.96). There was no association with acute Ijmphoblastic leukemia in children aged 1-6 years. The authors concluded that they had not confirmed the observation of an increased risk of childhood leukemia and cancer associated with intramuscular vitamin K. 

Central nervous system trauma, for example, post-stroke Metabolic disorders such as hjrperthyroidism Infectious diseases such as encephalitis Seizure disorders Central nervous system tumor... 

Coyle, T., Levante, S., Shetler, M., and Winfield, J. (1994). In vitro and in vivo cytotoxicity of gossypol against central nervous system tumor cell lines. /. Neurooncol. 19, 25-35. 

J. C. Panetta, M. N. Kirstein, A. Gajjar, G. Nair, M. Fouladi, R. L. Heideman, M. Wilkinson, and C. F. Stewart, Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors. Cancer Chemother Pharmacol 52 435 41 (2003). 

N.M. Bleehen, J.M. Ford (1993). Radiotherapy, hyperthermia, and photodynamic therapy for central nervous system tumors. Curr. Opin. Oncol, May 5-3, 458-463. 

A Bone marrow suppression (nadir at 4-6 weeks), pulmonary toxicity. IV. Short half life, crosses blood brain barrier. Central nervous system tumors, melanoma, and lymphomas. Most toxic alkylating agent. 

Ghosh C, Lazarus HM, Hewlett JS, Creger RJ. Fluctuation of serum phenytoin concentrations during autologous bone marrow transplant for primary central nervous system tumors. JNeurooncol (W92) 12, 25-32. 

Combined Modality Therapy of Central Nervous System Tumors... 

J. Klastersky, and P. Rocmans Combined Modality Therapy of Central Nervous System Tumors... 

Cobbs, C.S., Brenman, J.E., Aldape, K.D., Bredt, D.S., and Israel, M.A. (1995). Expression of nitric oxide synthase in human central nervous system tumors. Cancer Res. 55(4), 727-730. 

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