Cellulose, acid sulfate, carboxymethylation

The hemocompatibility of poly(amido-amine) polyelectrolyte complexes was recently studied by Xi, Zhang and coworkers [499, 500]. The poly(amido-amine) was based on piperazine and methylene bisacrylamide, and the polyelectrolyte complexes were obtained from the reaction of poly(amido-amine) with alginic acid, carboxymethyl cellulose or poly(methacrylic acid). Complexes of polyamido-amine and alginic acid with a 1 2 ratio gave the best hemocompatibility. Finally, the blood compatibility of polyelectrolyte complexes based on anionic and cationic cellulose derivatives were studied by Ito et al. [338], In vivo, good blood compatibility of complexes formed from quaternary hy-droxyethyl cellulose reacted with carboxymethyl cellulose and cellulose sulfate was observed. 

Hydrogenated palm kernel oil viscosity control agent, pharmaceutical topicals Isocetyl stearoyl stearate Laneth-15 Octyidodecyl stearoyl stearate PEG-150 distearate PEG-8 stearate Polyacrylic acid Tetradecyleicosanol Trihydroxystearin Triisostearyl trilinoleate Trilaneth-4 phosphate viscosity control agent, pharmaceuticals Ammonium sulfate Carboxymethyl hydroxyethyl cellulose Carboxymethyl hydroxypropyl guar Ceteareth-20 Glycol dilaurate... 

A complete list of semi-synthetic heparinoids is outside the scope of this article. Products of sulfation of neutral polysaccharides include sulfates of starch, cellulose, - - xylan, dextran, " guaran, and synthetic polymers of o-glucose. A somewhat closer simulation of the structure of heparin was attempted by sulfating polysaccharides containing amino sugars or uronic acids or both, such as chitin and chitosan, " and the corresponding N-formyl, N-(car-boxymethyl), O-(carboxymethyl), and 5-carboxylated - deriva-... 

Many PECs are prepared using chitosan as the polycationic component, therefore they will be discussed separately. Chitosan, the product of N-deacetylation of chitin, is one of the most commonly used cationic polymers of pharmaceutical interest due to its biocompatibility, nontoxicity, and mucoadhesivity. It is frequently used to form PECs, often in combination with alginate, carrageenan," hyaluronic acid, chondroitin sulfate (CS)," carboxymethyl cellulose (CMC), or poly(galacturonic acid), since these are natural anionic polysaccharides with favorable pharmaceutical properties. 

Sodium acrylate/vinyl alcohol copolymer Sodium carboxymethyl betaglucan Sodium carrageenan Sodium cellulose sulfate Sodium C4-12 olefin/maleic acid copolymer Sodium isooctylene/MA copolymer Sodium magnesium silicate Sodium polymethacrylate ... 

Diisobutyl phthalate Dimer acid, hydrogenated Nonoxynol-1 Nonoxynol-3 Polyethylene imine Sodium hydroxide cellophane, food packaging Acrylonitrile/styrene copolymer Aluminum myristates/palmitates Aluminum silicate Ammonium lauryl sulfate Ammonium oleate Ammonium stearate Ammonium sulfate Behenamide n-Butyl acetate Butylene glycol Calcium ethyl acetoacetate Calcium stearoyl lactylate Carboxymethyl hydroxyethyl cellulose Cellulose acetate butyrate ... 

HOBOCTbA Sulfate, sodium salt of fatty acids(C7-C9) with sodium hydrocarbon sulfonate and carboxymethyl cellulose Sodium allyl sulfonate about 40 %, sodium hydrocarbyl sulfonate 40-50 %, unsulfonated matter >140, moisture content >150 Prepared by sulfonating of fatty alcohols 1-2 % aqueous solution, mixed with sodium oleate and tar oil... 

Other possible components are a number of natural or naturally derived polymers such as carboxyamylose, carboxyamylopectin, carboxymaiman, carboxypullulan, carboxydextrans, carboxydextran sulfate, carboxycellulose, oxidized carboxymethyl-cellulose, and carboxyalginic acid. 

---