SODIUM CARBOXYMETHYL

Carboxymethylcellulose Sodium. Carboxymethyl ether of cellulose sodium salt (Citmcel) (8) is a white granular substance soluble in water depending on the degree of substitution. It is equally soluble in cold and hot water and may be prepared by treating alkaU cellulose with sodium chloroacetate. 

Sodium carboxymethyl cellulose [9004-32-4] (CMC) and hydroxyethyl cellulose [9004-62-0] (HEC) are the ceUulosics most widely used in drilling fluids (43). CMC is manufactured by carboxymethylation of cellulose which changes the water-insoluble cellulose into the water-soluble CMC (44). Hydroxyethyl cellulose and carboxymethyl hydroxyethyl cellulose (CMHEC) are made by a similar process. The viscosity grade of the material is determined by the degree of substitution and the molecular weight of the finished product. 

Sodium carboxymethyl chitin and phosphoryl chitin had most evident influences on the crystallization of calcium phosphate from supersaturated solutions. They potently inhibited the growth of hydroxyapatite and retarded the rate of spontaneous calcium phosphate precipitation. These chitin derivatives were incorporated into the precipitate and influenced both the phase and morphology of the calcium phosphate formed (flaky precipitate resembling octacalcium phosphate instead of spherical clusters in the absence of polysaccharide) [175]. 

The main polymers used as thickeners are modified celluloses and poly(acrylic acid). Several different modified celluloses are available, including methyl-, hydroxypropyl methyl-, and sodium carboxymethyl-cellulose and their properties vary according to the number and distribution of the substituents and according to relative molar mass of the parent cellulose. Hence a range of materials is available, some of which dissolve more readily than others, and which provide a wide spread of possible solution viscosities. Poly(acrylic acid) is also used as a thickener, and is also available in a range of relative molar masses which give rise to give solutions of different viscosities. 

Sodium carboxymethyl cellulose Poly(vinyl pryidine)... 

Sodium carboxymethyl cellulose (SS) Sodium cellulose sulfate (SS)... 

Fructose alone 2, fructose plus 0.25 % sodium carboxymethyl cellulose (CMC). 

Rossi et al. [30] evaluated rheologically mucins of different origin with polyacrylic acid and sodium carboxymethyl cellulose. The same group also reported a novel rheological approach based on a stationary viscoelastic test (creep test) to describe the interaction between mucoadhesive polymers and mucins [31,32]. Jabbari et al. [33] used attenuated total-reflection infrared spectroscopy to investigate the ehain interpenetration of polyaciylic acid in the mucin interface. 

Cellulose disintegrants have been studied as insoluble matrices for sustained release tablets. Anionically charged carboxymethyl cellulose (sodium salt) was found to be inferior to methyl cellulose and poly(vinyl pyrollidone) as a binding agent for oxyphenbutazone tablets [291], However sodium carboxymethyl cellulose has found application as a dispersing agent for ibuprofen microspheres... 

The bioadhesive characteristics of tablets for oral use made from modified starch, poly(acrylic acid), polyethylene glycol) and sodium carboxymethyl cellulose were recently investigated [406]. In this work, the force and energy adhesion were determined in vitro, and maximum adhesion times were evaluated in vivo in humans [406], In the in vitro, studies, the poly(acrylic add) gave the best performance, however in vivo bioadhesion was not strongly correletated with... 

Dosage form Regranex Gel is a non-sterile, preserved, sodium carboxymethyl-cellulose-based topical preparation containing becaplermin. Each gram of Regranex Gel contains becaplermin 100 pg. 

Typical granulating liquids are gelatin or sodium carboxymethyl cellulose solutions. 

Nitroglycol NC - Nitrocellulose MNT - Mononitrotoluene TNT - Trinitrotoluene Carbonaceous Materials, magenta), DAmmPh(Diammonium phosphate), NaCMC (Sodium carboxymethyl cellulose), Ca sulfate, Ca stearate, Gelatin) for unsheathed cartridges and in brackets for sheathed Charge limit in ounces - no ignition of gas by a... 

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