Capillary fragility

There are a number of signs and symptoms of essential fatty acid deficiency. They include scaly and thickened skin, alopecia, increased capillary fragility so that bruising readily occurs, poor wound healing, increased susceptibility to infection and growth retardation in infants and children. Some of these symptoms can be explained by deficiency of eicosanoid synthesis and/or failure to complete cell cycles in various tissues (Chapter 20). Consequently, it is important to detect a deficiency before symptoms develop. The principle underlying the method to do this is described ... 

Warfarin acts as a vitamin K antagonist and suppresses the hepatic formation of prothrombin and of factors VII, IX, and X, causing a markedly reduced prothrombin activity of the blood.Warfarin also causes dilatation and engorgement of blood vessels and an increase in capillary fragility. The two effects can combine to produce hematomas, severe blood... 

The dehciency disease associated with a lack of ascorbic acid is called scurvy. Early symptoms include malaise and follicular hyperkeratosis. Capillary fragility results in hemorrhages, particularly of the gums. Abnormal bone and tooth development can occur in growing children. The body s requirement for vitamin C increases during periods of stress, such as pregnancy and lactation. 

Capillary fragility, malaise, and abnormal bone and tooth development describe a deficiency of which vitamin ... 

It exerts its haemostatic action by reducing capillary fragility, and is indicated in epistaxis, haematuria, retinal... 

It is indicated for treatment of scurvy, for prophylaxis of vitamin C deficiency, to acidify urine, anaemia of vitamin C deficiency, as antioxidant to protect natural colour and flavour of many foods, dental caries and increased capillary fragility. 

Sophora japonica L. Huai Hua (Japanese pagoda tree) (flower bud) Rutin, sophoradiol, genisteine, sophoricoside, sophorabioside, sophoraflavonoloside, isorhammetin.33 252 Antihemostatic, increase capillary resistance and decreasing capillary fragility and permeability. 

The use of hydrothermally formed retaining frits in capillary columns packed with stationary phase particles is an accepted limitation in CEC. The introduction of the frit to hold the packed bed is vital, yet introduces problems such as EOF and flow non-uniformities, compromised frit permeability [87], capillary fragility, increased likelihood of bubble formation [88] and a thermally induced modified frit surface chemistry which can detrimentally alter the chromatography [23]. Practical aspects to be considered include the appreciable effort and skill of the analyst who is required to repeatably manufacture capillaries of a particular phase and redevelop the fritting and packing methodology for each different stationary phase type. 

Mian, E., Curri, S.B., Lietti, A., and BombardeUi, E., Anthocyanosides and the walls of the micro vessels further aspects of the mechanism of action of their protective effect in syndromes due to abnormal capillary fragility,. Minerva Medica, 68, 3563-3581, 1977. 

Blood diseases due to circulating antibodies, e.g. thrombocytopenic purpura (there may also be a decrease in capillary fragility with lessening of purpura even though thrombocytes remain few) agranulocytosis. 

The word flavonoid comes from Latin flavus, which means yellow, and included at the beginning only a yellow-colored group of compounds with a flavone nucleus (Jovanovic et al 1998). Today, the term is used in a broader context and includes colorless (flavan-3-ol) to less colored (flavanone) compounds, as well as the red and blue anthocyanins, all commonly occurring in plants. For a period, flavonoids were referred to as vitamin P because of their ability to decrease capillary fragility and permeability in humans. The term vitamin C2 has also been used, as it was known... 

The numerous health related properties of flavonoids, widely described in epidemiological studies, are mainly based on their antioxidant activities. These properties have been found to include anti-inflammatory and antiviral activities, effects on capillary fragility, inhibition of human platelet aggregation and anticancer activity. The antioxidant capacity of any flavonoid will be determined by a combination of the catechol structure in the B-ring, the 2,3-double bond in conjunction with a 4-oxo function, and the presence of both hydroxyl groups in positions 3 and 5. Due to their... 

Reduction of capillary fragility Aesculin Tested in pigs [155]... 

A recent paper (Reppert et al., 1951) has drawn attention to the remarkable speed with which ascorbic acid corrects the increased capillary fragility in scurvy. It is argued that this could hardly allow time for the repair of intercellular cement substance and suggests rather a direct chemical or enzymic response. Some experiments, reported in the barest outline, claim to show that ascorbic acid in large doses inhibits the hyaluronidase-hyaluronic reaction in rabbits and, to a small extent, in vitro. It is suggested that this inhibition of the spreading factor may account for the rapid improvement in capillary fragility. Obviously more experimental evidence is needed before this supposition can be seriously considered. 

Bismuth, capillary fragility and, VII, 33 Bisnorcholanic acid, eaters, infrared absorption spectra, VII, 316, 322, 323, 325 Bisnordeoxycholic acid, VIII, 267 configuration, VIII, 293 BlateUa germanica,... 

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