Capillary electrophoresis-mass spectrometry CE-MS

As in HPLC, the coupling of MS detection with CE has provided an excellent opportunity for more selective analysis, but the much reduced flow rates, small injection volumes, limitations in the types of buffers used [since electrospray ionization (ESI) is used in capillary electrophoresis/mass spectrometry (CE/MS)], and need to... 

The high-resolution power of capillary electrophoresis-mass spectrometry (CE-MS) makes it a powerful technique for the separation and analysis of charged metabolites however, only a few metabolomics applications have been published to date. Polypeptide fraction isolated from urine or plasma was analyzed by CE-MS and used to discriminate between coronary artery... 

Capillary electrophoresis mass spectrometry (CE-MS) Direct coupling of capillary electrophoresis (CE) and MS, where the mass spectrometer serves as the detector. Biomolecules are separated through the narrow capillary of the CE system and then interface with the MS for subsequent analysis. 

Surprisingly, not very many methods using the capillary electrophoresis-mass spectrometry (CE-MS) combination (mainly electrospray ionization) are in use in the area of forensic drug analysis. The first application of CE-MS for forensic purposes was described by Johansson et al. in 1991 [10] for the analysis of sulfonamides and benzodiazepines in urine. The main problem faced in this case is the need of improving the concentration sensitivity of the CE-MS combination. In order to improve the concentration of ana-... 

Capillary electrophoresis/mass spectrometry (CE/MS) is a useful tool for bioanalysis because it combines a highly efficient separation technique with a sensitive and selective detection system. Because CE offers excellent mass sensitivity but presents challenges when concentration sensitivity is needed, more sensitive detection systems are required. As an example of this, preliminary results for... 

In another application, Sturm et al. (44) evaluated CE-mass spectrometric (capillary electrophoresis-mass spectrometry [CE-MS]) data from different Corydalis species, that is, Corydalis cava from two different regions (CM and CB), Corydalis pumila (PU), Corydalis intermedia (IN), and Corydalis solida from two different regions (SG and SE). Exploring the CE-MS data with PCA succeeded in distinguishing the six Corydalis species samples. In this example, only a comprehensive list of peak areas of analytes was chosen as initial data... 

Capillary electrophoresis-mass spectrometry (CE-MS) combines the separating power of CE with the uniquely powerful detection capabilities of MS. This hyphenated system enables the analyst to separate, identify and quantify components in a mixture. As with GC-MS and LC-MS instruments, there is a variety of mass spectrometric ionisation techniques and analysers available. 

Capillary electrophoresis-mass spectrometry (CE-MS), 1033, 1182 Capillary gas chromatography, 3144 Capillary-like structures, 1446 Capillary zone electrophoresis (CZE), 1033, 1104, 1148, 1157 Caproic acid (CA), 2885 Caprylic acid (CAP), 2885 Capsaicin, 1456 Capsella bursa-pastoris, 864 Capsiate, 1458 Capsicum... 

Cell, tissue cultures, 2800 Cell-to-cell communication, 3525 Cellular adherence. I m Cellular cycle, 2960 Cellular systems, 215, 232, 245 Cellular toxicity, 1670 Cell walls, 1691, 1694, 1695 CE-MS. See Capillary electrophoresis-mass spectrometry (CE-MS)... 

This chapter will discuss methods for the analysis of many of these carbohydrate types using the newer methods of ionization, namely, matrix-assisted laser desorption/ionization (MALDI) and electrospray ionization (ESI). Recent reviews include those by Harvey," Zaia, Jang-Lee et al., Haslam et al., and Campa et al. [capillary electrophoresis/mass spectrometry (CE/MS)]. 

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