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Cancer Androgen

Breast cancer Androgen therapy may cause hypercalcemia by stimulating osteolysis. [Pg.237]

Breast Cancer. Androgens have been used to treat a limited number of hormone-sensitive tumors, such as certain cases of breast cancer in women. Other drugs such as the antiestrogens, however, have largely replaced the use of androgens in such cancers. The... [Pg.438]

LNCaP Human Prostate Cancer (androgen sensitive) ... [Pg.114]

Indications Metastatic prostate cancer, androgen-independent prostate cancer... [Pg.411]

Susceptibility factors Prostate cancer Androgen treatment of men has a striking number of champions, ready to spring to its defence whenever critics express reservations. That is the case regarding the widely expressed view [SEDA-30,477] that administration of androgens is undesirable in men with a history of prostatic cancer. In a recent review, Morgenthaler has argued... [Pg.871]

Atranorin (Bacidia stipata) Diffractaic acid (P. magellanica) Divaricatic acid (Protousnea malacea) Vicanicin (Psoroma malacea) Protolichesterinic acid (R. melanophthalma) Human prostate cancer androgen responsive (LNCaP) Human prostate cancer Androgen nonresponsive DU-145 Russo et al. (2012)... [Pg.131]

Glucocorticoids have inhibitory (apoptotic) effects on lymphocyte proliferation and are used to treat leukemias and lymphomas. Estrogens (fosfestrol) are used to block the effect of androgens in prostate cancer. Progestogens (megestrol, medroxyprogesteroneacetate) have been useful for treating endometrial carcinoma, renal tumors, and breast cancer. [Pg.155]

Hormone antagonists (tamoxifen and toremifen bind to the estradiol receptor, flutamide binds to the androgen receptor) are used for treating breast and prostate cancer. [Pg.155]

NAGATA C, TAKATSUKA N, SHIMIZU H, HAYASHI H, AKAMATSU T, MURASE K (2001) Effect of soymilk consumption on serum estrogen and androgen concentrations in Japanese men. Cancer Epidemiol Biomark Prev . 10 179-84. [Pg.84]

Cha, T.L. et al., Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth, Cancer Res., 65, 2287, 2005. [Pg.120]

Exemestane is an irreversible aromatase inactivator that binds to the aromatase enzyme to block the production of estrogen from androgens. Exemestane is absorbed rapidly after oral administration, with a terminal half-life of 24 hours. The drug is eliminated primarily by the liver and feces, with less than 1% of the dose excreted unchanged in the urine. Exemestane is indicated for the treatment of advanced breast cancer in postmenopausal women who have had disease progression following tamoxifen therapy. Side effects include hot flashes, fatigue, osteoporosis/bone fractures, and flulike symptoms. [Pg.1296]

Letrozole is another selective aromatase that inhibits the conversion of androgens to estrogen. Maximum plasma concentrations occur 1 hour after oral dosing concomitant food has not been shown to have an effect on the extent of absorption of letrazole. The terminal half-life is approximately 2 days. Letrozole is used in the treatment of postmenopausal women with hormone-receptor-positive or unknown advanced breast cancer. Side effects include bone pain, hot flushes, back pain, nausea, arthralgia, osteoporosis/bone fractures, and dyspnea. [Pg.1296]

Contrast the benefits and risks of luteinizing hormone-releasing hormone (LHRH) singleagent therapy and combined androgen blockade in the first-line therapy of metastatic prostate cancer. [Pg.1357]

See other pages where Cancer Androgen is mentioned: [Pg.178]    [Pg.280]    [Pg.378]    [Pg.1304]    [Pg.161]    [Pg.2030]    [Pg.573]    [Pg.101]    [Pg.135]    [Pg.178]    [Pg.280]    [Pg.378]    [Pg.1304]    [Pg.161]    [Pg.2030]    [Pg.573]    [Pg.101]    [Pg.135]    [Pg.221]    [Pg.445]    [Pg.447]    [Pg.442]    [Pg.91]    [Pg.93]    [Pg.93]    [Pg.108]    [Pg.118]    [Pg.123]    [Pg.65]    [Pg.218]    [Pg.219]    [Pg.221]    [Pg.1113]    [Pg.1117]    [Pg.1128]    [Pg.1128]    [Pg.1128]    [Pg.512]    [Pg.539]    [Pg.539]    [Pg.267]    [Pg.277]    [Pg.107]    [Pg.135]    [Pg.285]    [Pg.1316]    [Pg.1357]   


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