Butyric 3-chloro-3-methyl

CsHsClFOi 3-chloro-2-fluoro-butyric acid methyl ester 117970-99-7... 

CsHsClFOa 3-chloro-4-fluoro-butyric acid methyl ester 541-86-6... 

Chau and Terry [146] reported the formation of penta-fluorobenzyl derivatives of ten herbicidal acids including 4-chloro-2-methyl-phenoxy acetic acid [145]. They found that 5h was an optimum reaction time at room temperature with pentafluorobenzyl bromide in the presence of potassium carbonate solution. Agemian and Chau [147] studied the residue analysis of 4-chloro-2-methyl phenoxy acetic acid and 4-chloro-2-methyl phenoxy butyric acid from water samples by making the pentafluorobenzyl derivatives. Bromination [148], nitrification [149] and esterification with halogenated alcohol [145] have also been used to study the residue analysis of 4-chloro-2-methyl phenoxy acetic acid and 4-chloro-2-methyl phenoxybutyric acid. Recently pentafluorobenzyl derivatives of phenols and carboxylic acids were prepared for detection by electron capture at very low levels [150, 151]. Pentafluorobenzyl bromide has also been used for the analytical determination of organophosphorus pesticides [152],... 

Tetrahydrobenzo[6]thiophen-4-one (103) may be prepared from y-(2-thienyl)butyric acid by cyclization with phosphoric acid854 or by Friedel-Crafts cyclization of the corresponding acid chloride.194, 355.358 j s 5-methyl,357 2-ethyl,194 2-isopropyl,358 2- and 3-tert-butyl,359 2,3-dimethyl,360 2-ethyl-3-methyl,360 and 2-bromo 354 derivatives and diethyl 4,5,6,7-tetrahydrobenzo[6]thiophene-4,5-di-carboxylate861 may be prepared similarly. 4,5,6,7-Tetrahydrobenzo-[6]thiophen-7-one (104)357 362,863 and its 5- and 6-methyl 357 and 2-chloro 362 derivatives are obtained from the appropriately substituted y-(3-thienyl)butyric acid, A recent patent 364 describes the vapor phase cyclization of y-(2-thienyl)butyric acid to 103. Ketones (103 and 104) are useful intermediates for the synthesis of 4- and 7-substituted benzo[6]thiophenes, respectively their reactions are discussed in Section VI, B, 4. 

Phenoxyalkanoic acid herbicides are not amenable to direct gas chromatographic determination because of the high polarity or low volatility of the compounds and must be converted to their more volatile derivatives. The sensitivity of the electron capture detector towards alkyl esters of 4-chloro-2-methylphenoxy acetic acid, 4-chloro-2-methylphenoxy butyric acid, etc., is very poor. The methyl ester of 4-chloro-2-methylphenoxy acetic acid was 100 times less sensitive to electron affinity detection than the 2,4-D-methyl ester [396]. 

CHLORO-9-FLUORO-17-HYDROXY-16-bata-METHYL-, BUTYRATE 25122-57-0... 

Agemian and Chau [190] have reported a method for determining low levels of 4-chloro-2-methylphenoxyacetic acid and 4-(4-chloro-2-methylphenoxy)-butyric acid in non saline and waste waters by derivatisation with pentafluorobenzyl bromide. The increased sensitivity of the pentafluorobenzyl esters of these two herbicides over the 2-chloroethyl methyl esters as well as their longer retention times make pentafluoro-benzyl bromide the preferred reagent. 

Chemical Name (/CS )-a-cyano-3-phcnoxybcnzyl (/ S )-2-(4-chlorophenyl )-3-methyl butyrate cyano-(3-phenoxyphenyl)-methyl 4-chloro-a-(-1 -methylethyl)benzeneacetate Uses non-systemic insecticide to control a wide variety of pests and also used as acaricide CAS Registry No 51630-58-1 Molecular Formula C25H22C1N03 Molecular Weight 419.901 Melting Point (°C) liquid Boiling Point (°C) ... 

P-chloro-o-cresol is the precursor for the pesticides MCPA (2-methyl-4-chloro-phenoxyacetic acid), MCPP (2-methyl-4-chloro-phenoxy propionic acid) and MCPB (2-methyl-4-chloro-phenoxy butyric acid). MCPP is also known as mecoprop. 

Using indolyl-based substrate analogs such as 5-bromo-4-chloro-3-indolyl-ace-tate, butyrate, or propionate (X-acetate, X-butyrate, and X-propionate) for esterases and using the p-rosaniline assay coupled with ethanol, butanol, or propanol for alcohol dehydrogenases we were able to isolate several hundred candidates in the first level of a hierarchical screen. An intermediate screen was then used to characterize and compare the esterase candidates. We used nitrophenyl and methyl-umbelliferyl derivatives to analyze esterase candidates and their preference for chain length. 

An interesting effect was found whilst studying the enantioselectivity of these reactions. Although several esters (ethyl-2-chloropropionate, ethyl lactate, ethyl-2-hydroxy hexanoate and ethyl-2-methyl butyrate) were converted into the amides with only low to moderate ee values, the ammoniolysis of ibuprofen (2 -chloro-ethyl)ester was highly enantioselective. At 56 % conversion the ee of the remaining (S)-ester was 96% (Scheme 12.2-3), corresponding with an E value of the ammoniolysis of 28. 

Halogen in positions other than next to the carboxyl group of aliphatic acids is somewhat less reactive. For preparation of methyl 4-(diethylamino)-butyrate from the 4-chloro compound the detour through the 4-iodo compound was chosen, this being easily accessible by means of sodium iodide.521... 

Acrylate styrene acrylonitrile Acrylate modified styrene acrylonitrile Acrylic acid ester rubber Acrylonitrile butadiene rubber or nitrile butadiene rubber Acrylonitrile butadiene styrene Acrylonitrile styrene/chlorinated polyethylene Acrylonitrile methyl methacrylate Acrylonitrile styrene/EPR rubber or, acrylonitrile ethylene propylene styrene Alpha methyl styrene Atactic polypropylene Butadiene rubber or, cis-1,4-polybutadiene rubber or, polybutadiene rubber Butadiene styrene block copolymer Butyl rubber Bulk molding compound Casein formaldehyde Cellulose acetate Cellulose acetate butyrate Cellulose acetate propionate Cellulose nitrate Chlorinated polyethylene Chlorinated polyvinyl chloride Chloro-polyethylene or, chlorinated polyethylene. 

Synonyms 21 -Chloro-9-fluoro-17-hydroxy-16-methyl-pregna-1,4-diene-3,11,20-trione-17-butyrate 21 -chloro-11 -dehydrobetamethasone-17-butyrate Trade Names Emovate, Eumovate, Motivate Use Anti-inflammatory... 

Barcelo and co-workers [208] used negative ion electrospray MS as the detector in the analysis of eight acidic herbicides (benazolin, bentazone, 4-chloro-2-methyl-phenoxyacetic acid, 4-[4-chloro-2-methylphenoxy]butyric acid, 6- and 8-hydroxy-bentazone) in water. A C g column was used with a 30-min 20/80 —y 80/20 methanol/water (formic acid at pH 2.9) gradient. The detection limits were 0.03 pg/L. Co-elution of 6- and 8-hydroxybentazone occurred but these analytes were quantitated separately through the use of single ion monitoring (SIM). Excellent peak shapes were obtained and all other compounds were well resolved. 

Cl3H11N3, 3-Methyl-2-phenylimidazo[1,2-a]pyrimidine, 41B, 326 C13H13IN2, (E)-6-Methyl-6-azonia-2 -azastilbene iodide, 46B, 229 C13H14CINO2, Methyl 2-chloro-3-(indol-3-yl)butyrate, 44B, 237 C13H15NO3, Methyl 2-hydroxy-3-(indol-3-yl)butyrate, 44B, 237 C13H16N2O2, Melatonin, 40B, 249... 

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