Brain limbic

CYP2U1 mRNA expression in human thymus greater than heart and brain but similar in rats. WB shows protein in rat brain limbic, cortex, and thymus (Karigren et al., 2004). 

On intrathecal injection, it acts on substantia gelatinosa of dorsal horn of spinal cord and inhibit the release of excitatory transmitters. At supraspinal sites, it acts on medulla, mid brain, limbic and cortical areas. 

Mochida S, Westenbroek RE, Yokoyama CT, Zhong H, Myers SJ, Scheuer T, Itoh K, Catterall WA (2003) Requirement for the synaptic protein interaction site for reconstitution of synaptic transmission by P/Q-type calcium channels. Proc Natl Acad Sci USA 100 2819-24 Mongeau R, De Montigny C, Blier P (1994) Activation of 5-HT3 receptors enhances the electrically evoked release of [3H]noradrenaline in rat brain limbic structures. Eur J Pharmacol 256 269-79... 

Restricted localization of SCN5A to brain limbic pathways... 

Cortex mid-brain—limbic system reticular formation— vasomotor centres—>-reflex vessel tone pituitary- ACTH, etc. Nutrition ... 

The brain limbic system is an organ that is related to the emotional processing mechanism inside the mammalian brain. The limbic system is closely related to the functions of memory, emotional processing, and emotional learning (Picard 1997). The anatomical structure of the human limbic system is shown in Figure 1. 

The main components of brain limbic system are amygdala, orbitofrontal cortex, sensory cortex, and thalamus. This part of brain is involved in the emotional processing and learning (Bechara et al. 2000 Rolls 2000). In what follows, the primary components of the brain limbic system are briefly described and then a mathematical model of brain limbic system is introduced. Finally, the mathematical model is integrated with a PID and a semiactive inversion algorithm to develop a... 

A mathematical relationship between the components of brain limbic system was proposed by Moren and Balkenius (2000) from the descriptive physical model of the limbic system that provides a qualitative sense of the overall functioning of the system. Figure 2 shows the structure of the Moren-Balkenius computational BEL model. As depicted in the figure, the BEL model has four components of the so-called limbic system of the brain amygdala, orbitofrontal cortex, sensory cortex and thalamus. Of them, amygdala and orbitofrontal cortex perform an important function in emotional processing (Moren and Balkenius 2000). 

Kim, C., Langari, R. (2009). Target tracking control of a mobile robot using a brain limbic system based control strategy. Proceedings IEEE International Conference on Intelligent Robots and Systems, (pp. 5095-5064). St. Louis, MO IEEE. 

Serotonin (5-hydroxytryptamine, 5-HT) occurs in the intestinal wall, where it regulates motility and secretion in blood platelets, where it modulates platelet aggregation and vascular blood flow and in the CNS, where it acts as a neurotransmitter in areas of the midbrain. At least seven different receptors for serotonin have been characterized, which mediate a wide variety of different physiological effects. Depression and anxiety are thought to be the result of actions on 5-HTia receptors in the brain limbic system. Following release from neurons by a depolarizing action potential at central synapses, the activity of 5-HT is terminated by neuronal reuptake. This is performed by a synaptic membrane amine transporter protein, specific for 5-HT, which also co-transports sodium and chloride ions to repolarize the neuronal membrane. 

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