Bone marrow mononuclear cell fraction

Abbreviations BM-MNC, bone marrow mononuclear cell CABO, coronary artery bypass grafting CPC, circulating progenitor cells LV. left ventricle LVED. left ventricular end-diastolic diameter LVEDV, left ventricular end-diastolic volume LVEF, left ventricular ejection fraction NYHA, New York Heart Association SKMB, skeletal myoblast. 

Abbreviations AMI. acute myocardial infarction BM-MNC. bone marrow mononuclear cell LVEF, left ventricular ejection fraction SEM. standard error of mean TOPCARE-AMI, transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction MX. mesenchymal stem cell. 

Preparation of mononuclear cell fraction (MNC) from bone marrow (BM) harvests using a COBE 2991 cell processor... 

Endothelial progenitor cells can be isolated from the mononuclear fraction of the bone marrow or peripheral blood, as well as from fetal liver or umbilical cord blood [12, 23, 66, 67], Heterologous,... 

Adult bone marrow contains endothelial progenitor cells (EPCs) that are derived from hemangioblasts. EPCs can be mobilized from the bone marrow in response to systemic administration of angiogenic growth factors and cytokines, making it possible to isolate EPCs from the mononuclear fraction of rat, rabbit, and human peripheral blood. Embryonic stem cells can also be manipulated to differentiate into functional endothelial cells [18]. It has been hypothesized that one inciting event in the pathogenesis of neointimal hyper-... 

Tendera, M., Wojakowski, W., Ruzyllo, W., Chojnowska, L., Kepka, C., Tracz, W., Musialek, P. et al. 2009. Intracoronary infusion of bone marrow-derived selected Cd34-l- Cxcr4-l- cells and non-selected mononuclear cells in patients with acute Stemi and reduced left ventricular ejection fraction Results of randomized, multicentre myocardial regeneration by intracoronary infusion of selected population of stem cells in acute myocardial infarction (Regent) trial. Eur. Heart 30, 1313-1321. 

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