Biotextile

Another useful thermal characterization technique is thermal compression in which a polymer fabric or biotextile is subjected to different loads at different temperatures. The thickness, pore size, and distribution can be monitored at each condition to prepare ideal scaffolds for tissue engineering. PolyCethylene terephthalate) (PET) nonwoven fiber scaffolds have been prepared for tissue engineering by thermal compression and simultaneous characterization. Applying pressure near the T of the polymer ( 70°C) yielded better control of the pore size distribution and smaller pore sizes, which led to faster and wider proliferation of Irophoblast andNIH 3T3 cells on the scaffold [9]. 

Biotextiles as medical implants Edited byM. King andB. Gupta... 

In this work, biotextile antinucrobial medical plasters have been designed and developed by using the following two methods ... 

Over the past 20 years the editors of this book have developed a general definition for the term biotextiles . It has been derived from the consensus of experts who previously defined the related term biomaterials i ... 

Biotextiles are non-viable, permanent or temporary, fibrous textile structures created from synthetic or natural materials that are used either in an internal (inside the body) or external (outside the body) biological environment as a medical device for the prevention, treatment or diagnosis of an injury or disease, and as such, serve to improve the health, medical condition, comfort and wellness of the patient. 

Biotextile prostheses and closure products, such as surgical sutures, must have certain physical, mechanical and biological performance characteristics. There is a hierarchy of structure in developing these products, and thus their physical and mechanical performance as well as their chemical stability characteristics can be controlled by engineering the structure at the... 

Because there are always potential risks associated with any implantable device, before any new biotextile product can be distributed, sold and implanted clinically in a human patient in the United States, its properties and performance are required by law to be carefully reviewed and evaluated by the federal Food and Drug Administration. Its role is to ensure the safety and efficacy of all implantable devices before they are made available for surgical use in the United States. Other countries and jurisdictions have similar regulatory bodies that require all biotextile products to comply with their regulatory process (Chapter 7). 

Finally, Part I includes a chapter that discusses how implanted biotextile devices are retrieved from patients, either at autopsy or at reoperation, how the in vivo changes in properties and structure can be measured, how these changes can be Unked to the patient history and/or tied to premature failure, and using this knowledge, how to design and engineer the next generation of improved biotextile devices (Chapter 8). 

The chapters in Part II focus on various chnical applications of biotextile products, including details about the different devices, their therapeutic applications, their performance characteristics, current issues and shortcomings, active research emphasis and future prospects. An innovative use of resorbable polymers is in the dehvery of drugs, antimicrobials, growth factors and therapeutic agents. A detailed discussion of this is given in Chapter 9. 

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