Resorbable biotextile

A resorbable biotextile is a temporary supporting material in the human body its objective is to restore or repair the function of diseased or traumatized tissue. Several kinds of resorbable polymers are used for biotextUe applications. In suture application, glycolic and lactic add polymers are commercially used. Poly(glycolide-co-trimethylene carbonate), poly(glycolide-co-lactide-co-trimethylene carbonate), polydioxanone (Bourne, 1988), poly(lactide-co-caprolactone) (Tomihata, 1998) and polyhydroxyalkanoate (Voloka, 2003) have also been investigated for use as sutures. Natural polymers, such as chitin, chitosan and a benzyl ester of hyaluronic acid are... 

Rayleigh instability see axisymmetric varicose instability rayon, 4,6,18,20 recombinant silk fibres, 315-6 Recothrom, 581 relative density, 197 Relay devices, 661-2 resorbable biotextile, 94 resorbable polymers medical applications, 91-109 elastomeric properties of fibreforming copolymers, 97-101 elastomeric resorbable polymers, 101-8... 

As can be seen from the process flow chart (Fig. 3.1), in order to fabricate and assemble a resorbable biotextile device, a resorbable polymer has to withstand exposure to a range of potentially hazardous environments, such as thermal processing, mechanical abrasion, chemical treatment (lubricants, solvents, binders etc.), and atmospheric conditions, which include relative humidity. Each of these factors can drastically affect the rate of resorption and can cause premature degradation of the resorbable implant. 

The chapters in Part II focus on various chnical applications of biotextile products, including details about the different devices, their therapeutic applications, their performance characteristics, current issues and shortcomings, active research emphasis and future prospects. An innovative use of resorbable polymers is in the dehvery of drugs, antimicrobials, growth factors and therapeutic agents. A detailed discussion of this is given in Chapter 9. 

C. R. Gajjar and M. W. King, Resorbable Fiber-Forming Polymers for Biotextile Applications, SpringerBriefs in Materials,... 

In order to understand the resorption behavior of bioresorbable fibers and biotextiles when exposed to various processing parameters, it is necessary to understand the manufacturing processes for biotextiles. The majority of resorbable polymers are synthetic materials that have been engineered chemically to include hydrolysable groups. Hence, to begin with, most of these polymers are in the form... 

Some of the biomedical applications of each of the resorbable polymers have been discussed individually in the previous sections. Here, the general applications of fiber-forming bioresorbable polymers will be discussed. Table 7.1 shows the scope and range of biotextile devices currently used for medical applications. 

Resorbable Fiber-Forming Polymers for Biotextile Applications... 

---