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Biopolymer-Based Nanoparticles

Biopolymers are suitable materials as nanoparticles for clinical applications due to their versatile traits, including biocompatibility, biodegradability, and low immunogenicity. it is important to control particle size, charge, morphology of surface, and release rate of loaded molecules to use biopolymer-based nanoparticles as drug gene-delivery carriers. [Pg.651]


Valo H. Biopolymer-Based Nanoparticles for Drug Debvery. Finland Division of Pharmaceutical Technology, Faculty of Pharmacy, University of Helsinki 2012. [Pg.109]

Nitta, S. and K. Numata, Biopolymer-based nanoparticles for drug/gene delivery and tissue engineering. International Journal of Molecular Sciences, 14 (1) 1629-1654,2013. Kummitha, C.M., A.S. Malamas, and Z.R. Lu, Albumin pre-coating enhances intracellular siRNA delivery of multifunctional amphiphile/siRNA nanoparticles. International Journal of Nanomedicine, 7 5205-5214,2012. [Pg.263]

Allouche, J., Boissiere, M., Helary, C., Livage, J. and Coradin, T. (2006) Biomimetic core-shell gelatine/silica nanoparticles a new example of biopolymer-based nanocomposites. Journal of Materials Chemistry, 16, 3121-3131. [Pg.186]

This chapter provides an extensive overview concerning the effects of thermal degradation on various biopolymer based nanocomposites. It discusses the most recent developments/findings in relation to biopolymer based nanocomposites, in particular the effects of different nanoparticles on the thermal stability. Other issues regarding the research challenges, applications and future trends are also addressed in this chapter. [Pg.226]

Fig. 17 (a) Elastin-based stimulus-responsive gold nanoparticles. Reproduced from [131] by permission of The Royal Society of Chemistry (b) Functionalization of a glass surface with ELP. In the first step, the glass surface is aminosilylated with N-2-(aminoethyl)-3-aminopropyl-trimethoxysilane, then modified with glutaraldehyde. Subsequently, the stimulus-responsive biopolymer is covalently immobilized using reductive amination. Reproduced from [132] by permission of The Royal Society of Chemistry... [Pg.93]

Jung SW, Jeong Yl, Kim YH, Kim SH. Self-assembled polymeric nanoparticles of poly(ethylene glycol) grafted pullulan acetate as a novel drug carrier. Arch Pharmacal Res 2004 27(5) 562-569. Peppas NA. Devices based on intelligent biopolymers for oral protein delivery. Int J Pharm 2004 277(1-2) 11-17. [Pg.550]

AppticATioN OF Cellulose-Based Biopolymer 28.6.3.1 Nanoparticles in Drug and Bioactive Delivery... [Pg.560]


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