Aminopropyl trimethoxysilane

Fig. 17 (a) Elastin-based stimulus-responsive gold nanoparticles. Reproduced from [131] by permission of The Royal Society of Chemistry (b) Functionalization of a glass surface with ELP. In the first step, the glass surface is aminosilylated with N-2-(aminoethyl)-3-aminopropyl-trimethoxysilane, then modified with glutaraldehyde. Subsequently, the stimulus-responsive biopolymer is covalently immobilized using reductive amination. Reproduced from [132] by permission of The Royal Society of Chemistry... 

Immobilized Bronsted Acids Supported Fluorosulphuric Acid (FSOsH/SiOA and Trifluoroacetic Acid (CFsCOOH/SiOA- 1.6 mmoles of (3-aminopropyl) trimethoxysilane was dissolved in 100 mL of chloroform, and 1 g of silica gel was added. The slurry was heated under reflux for 24 h. The slurry... 

In this work, we have grafted the mesoporous SBA-15 materials with 3-aminopropyl trimethoxysilane [10], In a subsequent step, the aminopropyl moiety was reacted with glutardialdehyde, which reacts also with amino groups of the enzymes chloroperoxidase (CPO) and glucose oxidase (GOx) (Scheme 1). 

Several different analytical and ultra-micropreparative CEC approaches have been described for such peptide separations. For example, open tubular (OT-CEC) methods have been used 290-294 with etched fused silicas to increase the surface area with diols or octadecyl chains then bonded to the surface.1 With such OT-CEC systems, the peptide-ligand interactions of, for example, angiotensin I-III increased with increasing hydrophobicity of the bonded phase on the capillary wall. Porous layer open tubular (PLOT) capillaries coated with anionic polymers 295 or poly(aspartic acid) 296 have also been employed 297 to separate basic peptides on the inner wall of fused silica capillaries of 20 pm i.d. When the same eluent conditions were employed, superior performance was observed for these PLOT capillaries compared to the corresponding capillary zone electrophoresis (HP-CZE) separation. Peptide mixtures can be analyzed 298-300 with OT-CEC systems based on octyl-bonded fused silica capillaries that have been coated with (3-aminopropyl)trimethoxysilane (APS), as well as with pressurized CEC (pCEC) packed with particles of similar surface chemistry, to decrease the electrostatic interactions between the solute and the surface, coupled to a mass spectrometer (MS). In the pressurized flow version of electrochromatography, a pLC pump is also employed (Figure 26) to facilitate liquid flow, reduce bubble formation, and to fine-tune the selectivity of the separation of the peptide mixture. 

The chemical entrapment of TEMPO moiety in the sol-gel silica hybrid material is performed in two steps reductive amination of 4-oxo-TEMPO with 3-aminopropyl-trimethoxysilane (APTMS) followed by sol-gel co-poly-condensation of the TEMPO-funcionalized alkoxide thereby obtained with methyl-trimethoxysilane (MTMS) catalyzed by fluoride (Figure 6.2). 

P-cyclodextrin (P-CD) was supplied by Roquette Freres (France). (3-aminopropyl) trimethoxysilane (97%) (APS), tetraethyl orthosiUcate (99.999%) (TEOS) and N,N-dimethylacetamide (99%) (DMAc) were purchased from Aldrich and used without further purification. Sodium dodecylsulfate (>97%) (SDS) was obtained from Fluka. Para-nitrophenol (99%) (p-NP) was supplied by Acros Organics and lead(II) nitrate (99.99%) by Sigma. 

Then, in a tricol, heated at 303 K under nitrogen, 5g (0.004 mole) of P-CDOTs were dissolved in 125 mL of DMAe (kept previously on molecular sieves) until the solution cleared. 7 mL (0.04 mole) of (3-aminopropyl)trimethoxysilane (APS) were added drop wise. The solution was vigorously stirred for 1 hour and then precipitated in 1.4 L of acetone (distilled twice, on molecular sieves). The white precipitate was kept under stirring for 2 hours and filtered. The product obtained (P-CDAPS) was dried 2 days at 353 K under vacuum and crushed to form homogeneous yellow powder. The reaction scheme expected is presented on Fig. 1. Si, N, C, N, H contents were determined by TGA, amine titration and elemental analysis. 

SYNS (N-(3-AMINOPROPYL)-3-AMINOPROPYL)-TRIMETHOXYSILANE 1,3-PROPANEDIAMINE, N-(3-(TRIMETHOXYSILYL)PROPYL)- SILANE 40-47... 

Commercially available tetraethyl orthosilicate (TEOS), dodecyltrimethyl- ammonium chloride (DTMACl) and trimethylammonium hydroxide (TMAOH) were mixed in water and the solution was stirred for 4 h at room temperature. The composition of the gel mixture was Si DTMACl TMAOH H2O = 1 0.6 0.3 60. White precipitates were filtered and dried at 393 K. This as-synthesized powder was calcined at 903 K for 4 h to obtain MCM-41. The silica was stirred vigorously in toluene containing a monolayer equivalent amount (1.0 per 1 nm ) of [l-(2-aminoethyl)-3-aminopropyl]trimethoxysilane... 

Pang12831 successfully synthesized millimeter-sized mesoporous Co-SiC>2 spheres through the introduction of Conl-(3-aminopropyl)trimethoxysilane (APTMOS) complex into the reaction mixture with CTAB as template in basic media. The mesoporous Co-Si02 spheres have a high surface area and disordered pores. 

Figure 5.11 AFM images of PS-i)-P4VP-[Re(DIAN)(C0)3]+C10j spin-coated on different substrate surfaces (film thickness = 40 nm) (a) silicon wafer modified with (3-aminopropyl)trimethoxysilane (b) silicon wafer modified with A-trimethoxysilylpropyl-AyV,lV-trimethylammonium chloride (c) silicon wafer modified with 3-(p-methoxyphenyl)propyltrichlorosilane and (d) silicon wafer with native oxide layer removed. All the films were prepared from toluene solution. Scan size (a)- c) 1X1 pm (d) 500 X 500 nm. (From Cheng and Chan.71 Reprinted with permission. Copyright 2005 American Chemical Society.)...

The first surface-initiated enzymatic polymerization reported was the synthesis of amylose brushes on planar and spherical surfaces [69]. For this silica or silicone surfaces were modified with self-assembled monolayers of (3-aminopropyl) trimethoxysilane or chlorodimethylsilane respectively. To these functionalities oligosaccharides were added via (a) reductive amidation of the oligosaccharides... 

In the first, developed by usj a layer of clay mineral particles is covered with the cationic polyelectrolyte poly(diallyldimethylammoniumchloride) (PDDA) and subsequently with the anionic, noncentrosymmetric dye 4- 4[A -allyl,A -methylamino]phenylazo benzene sulpho-nic acid (NAMC). Thus, the monolayer consists of clay/ PDDA/NAMO. It is supported on a glass substrate, derivatized with 3-aminopropyl-trimethoxysilane (APTS)... 

Chem. Descrip. N-[2-(Vinylbenzylamino)-ethyl]-3-aminopropyl trimethoxysilane in methanol... 

Aminoethyl) aminopropyl) trimethoxysilane. See N-2-Aminoethyl-3-aminopropyl trimethoxysilane... 

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