Biodegradation, programmed

Williams RT, Ziegenfuss PS, Marks PJ. 1989. Installation restoration program environmental technology department. Biodegradation of DIMP, dieldrin, isodrin, DBCP, and PCPMSO in the RMA soils. West Chester, PA Roy F. Weston, Inc. NTIS No. AD-A245-852. 

Norway has a standardized test program for permit derivation, comprising the Ames mutagenicity test, acute and chronic toxicity tests, and a biodegradation test. For monitoring purposes, it is advised to start screening the toxicity of an effluent with a comparatively large... 

The META system (291-293) is an expert system, based on well-established sources, for predicting the sites of potential enzymatic attack and the metabolites formed by metabolic transformations. The program uses dictionaries of biotransformation operators, which are created by experts to represent known metabolic paths. Currently, META can be combined with one of the following dictionaries mammalian metabolism, aerobic biodegradation, anaerobic biodegradation, and metabolic transformation reactions (291). 

Dry environmental quality PetroKlenz must be reconstituted with water and made into a slurry. The organisms will be ineffective if they are applied as dry cultures over the oil. The effective use of PetroKlenz in a biotreatment program is dependent upon the environmental conditions present at the site. Adverse conditions such as cold temperatures, oxygen, nitrogen, or phosphorus-deficient water, chemical toxic load, highly acidic or alkaline conditions, or excessive dilution of biomass by tides and currents, may retard or prevent biodegradation. 

The conditions in parentheses tabulated by Gamberger et al. are merely a mathematical expression by which a computer program can readily assess a structure and make a prediction as to whether it is expected to biodegrade. If the molecule should fulfill any of the conditions, then it is predicted to biodegrade readily. For example, if we take condition BVI (Table 7.5), this condition is fulfilled by a molecule made up of the elements , H, N, and but without any nitro groups, has no more than one ring, at least one C-0 bond, no more than two C=C bonds, and no quaternary centers or tertiary amino groups. 

Howard, P.H. and Meylan, W.M. Biodegradation Probability Program, Syracuse Research Corporation, Syracuse, NY (1992). 

The newest biodegradation models in EPI Suite are BioHCwin and BIOWIN7. BioHCwin is a separate program from BIOWIN and estimates the logarithm of the... 

Predicted using battery method IF the BIOWIN3 (ultimate survey model) result is weeks or faster (i.e., days , days to weeks , or weeks AND the BIOWIN5 (MITI linear model) probability is > 0.5, then the prediction is RB (readily biodegradable). If this condition is not satisfied, the prediction is NRB (not readily biodegradable). BIOWIN3 and -5 are in the BIOWIN program v4.10 (in EPI Suite v4.00). See Section 16.3.3. 

Suite, the PBT Profiler, and the BIOWIN biodegradability estimation program. He is the recipient of many EPA medals for distinguished service and several EPA Science and Technology Achievement Awards (STAA), including awards for review of new chemical substances under TSCA and the Handbook of Property Estimation Methods for Chemicals Environmental Health Sciences (Lewis/CRC, 2000, with Don Mackay). 

Harkness, M. R. Bergeron, J. A. (1990). Availability of PCBs in soils and sediments to surfactant extraction and aerobic biodegradation. In Ninth Progress Report for the Research and Development Program for the Destruction of PCBs, pp. 109-20. Schenectady, NY General Electric Co. Corporate Research and Development. 

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