Bacterial “cleansing

Utilising the usual levels of anti-microbials for cleansing products with normal user instructions of three minutes or longer contact time can achieve positive claims of anti-bacterial for Myavert C based enzyme preservation system without the stinging associated with alcohol. Table 1 gives the plate kill speed data for a face masque where the preservative also becomes a positive attribute. 

The same principle is used for face washes using Myavert C to cleanse the face of bacteria, without the stinging associated with other forms of anti-bacterial face wash. 

Treatment for herpes genitalis is only indicated in serious or frequently recurring disease, in the presence of immunodepression or if psychosocial circumstances dictate this. Primary and recurrent infection is treated for 5 days with an oral derivative of aciclovir, either valaciclovir 2 x 500 mg or famciclovir 3 x 250 mg. Partial or complete aciclovir resistance may develop. Prophylactic aciclovir may be indicated if the frequency of recurrence is >6 per year. Local care of lesion (cleansing, disinfecting creams) is indicated to prevent secondary bacterial infection. 

Act by precipitating bacterial proteins. Effective antiseptic cleansing agent at 40-90% concentration (above 70% antiseptic up to 90%). 

Ansari, S., Scala, D., Kaplan, S., Jones, K., Ghaim, J., and Polefka, T., A novel skin cleansing technology that reduces bacterial attachment to the skin, Abstr. Gen. Meet. Am. Soc. Microbiol., 102, 399, 2002. 

Bacterial impermeability has a dual role. The wound will not heal if it is heavily infected. The inflammatory phase will be extended, and, unless topical or systemic antibacterial agents are used, a more general infection could result. However, a limited number of microorganisms are tolerated by most wounds, and the destructive or cleansing phase produced by phagocytic activity should result in a self-sterilized environment. The wound should be protected from secondary infection or, if still contaminated, be prevented from transmitting the infective organisms. 

B Price. The bacteriology of normal skin a new quantitative test applied to a study of the bacterial flora and the disinfectant action of mechanical cleansing. J Infect Dis 63 301-318, 1938. 

Aliphatic alcohols such as ethanol, n-propanol, n-butanol and isopentyl (isoamyl) alcohol exert disruptive effects upon bacterial membranes as shown by the lysis of protoplasts [76]. Of these, only ethanol displays any useful bactericidal activity it is used to cleanse the skin before injections and to sterilize instruments. Butanol is used to solubilize membrane-bound enzymes [22,91], its action being similar to that of the non-ionic detergents described below. 

The use of topical corticosteroids, used in the successful treatment of ACD, has been questioned as a treatment for irritant dermatitis (van der Valk and Maibach 1989). They may be effective in chronic, hyperkeratotic irritant dermatitis, but their prolonged use may lead to epidermal atrophy and, consequently, increased irritant sensitivity. Other therapeutic options in irritant dermatitis include topical tars and phototherapy (ultraviolet B or psoralen plus ultraviolet A). In difficult cases of chronic, irritant hand dermatitis, radiation may be indicated (Goldschmidt and Pan-izzon 1991). Bacterial superinfection may be a complication of contact dermatitis it is treated with topical or systemic antibiotics. Potential irritants, such as irritant cleansing products, must be identified and (whenever possible) eliminated, not only in the workplace but in the home (Frosch 1989). 

Carious-like lesions can be produced in extracted human teeth by exposure to a nutrient medium suitable for bacterial growth and by innocula-tion of the solution with oral microorganisms. Lesions were produced in the early work of E. Magitot (around 1870) and later by W. D. Miller and many subsequent research workers 110). In vitro studies of this type have been greatly improved by the introduction of the Artificial Mouth in which many of the important oral conditions are reproduced. Under appropriate conditions, the entire tooth structure will be destroyed. In order to produce localized lesions, regular cleansing of the exposed tooth surfaces is required (111). 

T. W. Heath, Benjamin Parker Coffindaffer, and S. D. Kyte, Kenneth Eugene Smith, Edward Dewey McConaughy, Personal cleansing compositions comprising bacterial cellulose network and cationic polymer. 

Wermeister [310] described a technique, utilizing ozone gas of 80-100 Xg/ml concentration, for wound cleansing and disinfection. Such an effect has not been observed during enz5mie treatment. Often, the bacterially infected spot is washed out by ozone-oxygen mixture, which gives certain positive effect. 

---