Chemotaxis, bacterial

Parales, R. E. and Harwood, C. S. (2002). Bacterial chemotaxis to pollutants and plant-derived aromatic molecules, Curr. Opin. Microbiol., 5, 266-273. 

Marx, R. B. and Aitken, M. D. (2000). Bacterial chemotaxis enhances naphthalene degradation in a heterogeneous aqueous system, Environ. Sci. Technol., 34, 3379-3383. 

Eukaryotic ABC transport system Phosphotransferase system (PTS) Ion-coupled transport system Signal Transduction Two-component system Bacterial chemotaxis MAPK signaling pathway Second messenger signaling pathway Ligand-Receptor Interaction G-protein-coupled receptors Ion-channel-linked receptors Cytokine receptors Molecular Assembly Ribosome assembly Flagellar assembly Enzyme assembly... 

Jurica MS, Stoddard BE. 1998. Mind your B s and R s bacterial chemotaxis, signal transduction and protein recognition. Structure 6 809-13. 

Xiong J, Kurtz DM Jr, Ai J, Sanders-Loehr J. 2000. A hemerythrin-like domain in a bacterial chemotaxis protein. Biochemistry 39 5117-25. 

D. Bray, R. B. Bourret, andM. I. Simon, Computer simulation of the phosphorylation cascade controlling bacterial chemotaxis. Mol. Biol. Cell, 4, 469 82 (1993). 

Hess, J.F. Bourret, R.B. Simon, M.L Histidine phosphorylation and phosphoryl group transfer in bacterial chemotaxis. Nature, 336, 139-143 (1988)... 

McEvoy, M.M. Hausrath, A.C. Randolph, G.B. Remington, S.J. Dahl-quist, F.W. Two binding modes reveal flexibility in kinase/response regulator interactions in the bacterial chemotaxis pathway. Proc. Natl. Acad. Sci. USA, 95, 7333-7338 (1998)... 

Oosawa, K. Hess, J.R Simon, M.L Mutants defective in bacterial chemotaxis show modified protein phosphorylation. Cell, 53, 89-96 (1988)... 

Stock, A. Ghen, T. Welsh, D. Stock, J. CheA protein, a central regulator of bacterial chemotaxis, belongs to a family of proteins that control gene expression in response to changing environmental conditions. Proc. Natl. Acad. Sci. USA, 85, 1403-1407 (1988)... 

FIGURE 12-26 The two-component signaling mechanism in bacterial chemotaxis. When an attractant ligand (A) binds to the receptor domain of the membrane-bound receptor, a protein His kinase in the cytosolic domain (component 1) is activated and autophosphorylates on a His residue. This phosphoryl group is then transferred to an Asp residue on component 2 (in some cases a separate protein in others, another domain of the receptor protein). After phosphorylation on Asp, component 2 moves to the base of the flagellum, where it determines the direction of rotation of the flagellar motor. 

Carboxyl groups of certain glutamate side chains in proteins that control bacterial chemotaxis are methylated reversibly to form methyl esters.130 This carboxylmethylation occurs as part of a reaction sequence by which the bacteria sense compounds that can serve as food or that indicate the presence of food... 

The sensor protein is NtrB (NRn), which is an auto-phosphorylating histidine kinase similar to the CheY protein of bacterial chemotaxis (Fig. 19-5). 

Standard models for bacterial chemotaxis are based on the behavior of nonmarine enteric bacteria.196 Chemotactic behavior of nonmarine bacteria consists of discrete steps of short runs interspersed with tumbling, resulting in the random repositioning of the cells, i.e., the classical random walk. As a consequence, the net speed up a chemical gradient via the random-walk response is only a few percent of the swimming speed. The relatively slow speed and mode of chemotaxis displayed by nonmarine enteric bacteria would restrict the ability of marine bacteria to respond to chemical gradients in the sea and hence cast doubt on the importance of chemotaxis for bacteria in turbulent marine environments. 

Blackburn, N. and Fenchel, T., Influence of bacteria, diffusion and shear on micro-scale nutrient patches, and implications for bacterial chemotaxis, Mar. Ecol. Prog. Ser., 189, 1, 1999. 

Zimmer-Faust, R. K., de Souza, M. P., and Yoch, D. C., Bacterial chemotaxis and its potential role in marine dimethylsulfide production and biogeochemical sulfur cycling, Limnol. Oceanogr., 41, 1330, 1996. 

Koshland, D. E., Bacterial Chemotaxis as a Model Behavioral System, Distinguished Lecture Series of the Society of General Physiologists, Vol. 2, Raven Press, New York, 1980. 

Clarke, S. and Koshland, D. E., Membrane receptors for aspartate and serine in bacterial chemotaxis, J. Biol. Chem. 254, 9695, 1979. 

Yi, T. M., Huang, Y., Simon, M. I., and Doyle, J., Robust perfect adaptation in bacterial chemotaxis through integral feedback control, Proc. Natl. Acad. Sci. USA, 97, 4649, 2000. 

In a model borrowed from the study of bacterial chemotaxis, it was initially proposed that OBPs not only solubilize specific pheromones, but trigger the olfactory receptors when bound to odorant molecules (Pelosi, 1994). Later, it was further hypothesized that electrostatic and hydrophobic interactions from both the bound ligand and ligated protein are necessary and sufficient for receptor activation (Prestwich and Du, 1997). To the best of my knowledge the protein-ligand complex model has never been tested in bacteria. Certainly, it is not... 

Koshland, D. E. Jr. A model regulatory system bacterial chemotaxis. Physiol Rev 1979, 59 811-862. 

Kim, S.-H. et al. (2002). Dynamic and clustering model of bacterial chemotaxis receptors Structural basis for signaling and high sensitivity. Proc. Natl. Acad. Sd. 99, 11611-11615. 

Pandey, G. and Jain, R.K. 2002. Bacterial chemotaxis toward environmental pollutants Role in bioremediation. Applied Environmental Microbiology, 68 5789-95. 

Bacterial Chemotaxis Depends on Reversal of the Direction of Flagellar Rotation... 

R.M. Macnab and D.E. Koshland Jr. 1972. The gradient-sensing mechanism in bacterial chemotaxis Proc. Natl. Acad. Sci. USA 69 2509-2512. (PubMedl... 

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