Babinski reflex

Death from overdose of barbiturates may occur and is more likely when more than 10 times the hypnotic dose is ingested. The barbiturates with high lipid solubility and short half-lives are the most toxic. Thus the lethal dose of phenobarbital is 6—10 g, whereas that of secobarbital, pentobarbital, or amo-barbital is 2-3 g. Symptoms of barbiturate poisoning include CNS depression, coma, depressed reflex activity, a positive Babinski reflex, contracted pupils (with hypoxia there may be paralytic dilation), altered respiration, hypothermia, depressed cardiac function, hypotension, shock, pulmonary complications, and renal failure. 

The common symptoms are tingling of the hands, gradually increasing sensory disturbances, and finally motor disturbances, usually of the hands, although only after thalidomide has been taken over a lengthy period. A positive Babinsky reflex and disturbed vibration sense have also been reported (39). Unless the drug is discontinued promptly at the start of symptoms the polyneuropathy can be irreversible (40,41). 

Organic Mercury. Exposure to unspecified alkyl mercury compounds has caused muscular effects (e.g., muscle fasciculations, absence of deep reflexes in arms, Babinski reflex) (Brown 1954 Hook et al. 1954 ... 

Neurodevelopment At birth, newborn assessments (e.g. suckling, Babinski, and startle reflexes)... 

Motor symptoms are less common, but loss of fine motor movements frequently develops for example, the dexterity required for playing a musical instrument, or doing and undoing buttons. Tremor and myoclonus are rare. Gait may become hesitant and slow, and patients may lose balance. Deep tendon reflexes in the lower extremities become brisk, and occasionally a Babinski sign or other pyramidal release sign may be observed. 

Sudden onset hemiparesis with tendon reflex asymmetry and positive Babinski sign... 

Somnolent but reusable, confused Disorientation for place, aggressive Asterixis, hyperactive reflexes, Babinski s sign, muscle rigidity Triphasic waves (5 cycles/s)... 

Reflexes Biceps, triceps, tendon reflexes, plantar response (Babinski sign is an upgoing toe and is abnormal), superficial cutaneous reflexes (abdominal) Stroke, spinal cord lesions, endocrine diseases (e.g., diabetes, hypothyroidism), peripheral neuropathy... 

Polyneuritis, tremors, paresthesias of hands and feet, retrobulbar neuritis, painful extremities, cranial nerve palsies, optic neuropathy, flaccid paralysis, choreiform movements, myoclonic movements of head and extremities, sensory neuropathy, ascending weakness, optic neuritis and blindness, abnormal reflexes, Babinski s reflex, residual weakness, visual problems Skin eruptions, hepatorenal injury, bone marrow depression, alopecia, hypertension, achlorhydria, stomatitis, excessive salivation, gingival discoloration, tachycardia, arrhythmias, weakness... 

Lungs and chest, not including breast examination. Abnormal chest wall expansion, abnormal respiratory rate, abnormal breath sounds including wheezes or alveolar rales, impaired respiratory function, cyanosis, 12. Neurological Impaired equilibrium, coordination or speech pattern asymmetric deep tendon reflexes, sensory or positional abnormalities, abnormal patellar and Babinski s rellexes. ... 

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