Atmospheric pressure ionization time-of-flight

A. F. Dodonov, I. V. Chernushevich, and V. V. Laiko. Atmospheric Pressure Ionization Time-of-Flight Mass Spectrometer (Abstr). 12th International Mass Spectrometry Conference, 26-30 August, 1991, Amsterdam, the Netherlands, 153. [Pg.82]

C. H. Sin, E. D. Lee, and M. L. Lee. Atmospheric Pressure Ionization Time-of-Flight Mass Spectrometry with a Supersonic Ion Beam. Anal. Chem., 63(1991) 2897-2900. [Pg.82]

Atmospheric pressure ionization time-of-flight mass 1996 APETOF MS 0.01 [26, p. 54]... [Pg.29]

Zhang, H., Heinig, K., and Henion, J. (2000). Atmospheric pressure ionization time-of-flight mass spectrometry coupled with fast liquid chromatography for quantitation and accurate mass measurement of five pharmaceutical drugs in human plasma. J. Mass Spectrom. 35 423-431. [Pg.250]

N Zhang ST Fountain, H Bi, DT Rossi. Quantification and rapid metabolite identification in drug discovery using atmospheric pressure ionization time-of-flight LC/ MS. Anal Chem 72 800—806, 2000. [Pg.83]

Zhang H, Henion J, Yang Y, Spooner N. Application of atmospheric pressure ionization time-of-flight mass spectrometry coupled with liquid chromatography for the characterization of in vitro drug metabolites. Anal Chem 2000a 72 3342-3348. [Pg.447]

Chen X, Hu L, Su X, Kong L, Ye M, Zou H. Separation and detection of compotmds in honeysuckle by integration of ion-exchange chromatography fractionation with reversed-phase liquid chromatography—atmospheric pressure chemical ionization mass spectrometer and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis. J Pharm Biomed Anal 2006 40 559-70. [Pg.539]

GC-FID, gas chromatography flame ionization detection GCMS, gas chromatography mass spectrometry APcI-TOFMS, atmospheric pressure chemical ionization-time of flight mass spectrometry PTRMS, proton-transfer-reaction mass spectrometry. [Pg.337]

Various analyzers have been used to analyze phenolic compounds. The choice of the MS analyzer is influenced by the main objective of the study. The triple quadrupole (QqQ) has been used to quantify, applying multiple reaction monitoring experiments, whereas the ion trap has been used for both identification and structure elucidation of phenolic compounds. Moreover, time-of-flight (TOF) and Fourier-transform ion cyclotron resonance (FT-ICR) are mainly recommended for studies focused on obtaining accurate mass measurements with errors below 5 ppm and sub-ppm errors, respectively (Werner and others 2008). Nowadays, hybrid equipment also exists, including different ionization sources with different analyzers, for instance electrospray or atmospheric pressure chemical ionization with triple quadrupole and time-of-flight (Waridel and others 2001). [Pg.60]

Jarvis, S. A., Bateman, R. H., Carruthers, R., Doorbar, P., and Green, M. (1998). A new atmospheric pressure ionization orthogonal acceleration time of flight mass spectrometer. Adv. Mass Spectrom. 14, B044120/1-B044120/7. [Pg.513]

Notes AA, acetic acid AAc, ammoniuin acetate ACN, acetonitrile AH, airnnonium hydroxide FA, formic acid MeOH, methanol TFA, trifluoroacetic acid THF, Tetrahydrofuran APCI, atmospheric pressure chemical ionization APPI, atmospheric pressure photoionization ESI, electrospray ionization IS, ion spray IT, ion trap Q, single quadrupole QqQ, triple quadrupole TOF, time of flight. [Pg.93]

LLE liquid-liquid extraction, SPE solid phase extraction, LPME liquid-phase microextraction, ESI electrospray ionization, APCI atmospheric pressure chemical ionization, SSI sonic spray ionization, Q quadrupole, QqQ triple quadrupole, TOF time-of-flight, IT ion trap, IS internal standard, CV coefficient of variation, MRE mean relative error, LOD limit of detection, LLOQ lower limit of quantification... [Pg.159]

FIGURE 11.1 A generalized flow scheme that indicates the fundamental elements of LC-MS-based bioanalysis. Abbreviations LLE = liquid-liquid extraction SPE = solid-phase extraction RAM = restricted-access media TEC = turbulent flow liquid chromatography API = atmospheric-pressure ionization APCI = atmospheric-pressure chemical ionization ESI = electrospray ionization SQMS = single-quadrupole mass spectrometry TQMS = triple-quadrupole mass spectrometry TOF = time-of-flight Q-TOF = quadrupole TOF. (Reprinted from Ackermann et al. [4], with permission from John Wiley Sons, Inc.)... [Pg.318]

Steiner, W.E. Clowers, B.H. English, W.A. Hill, H.H., Jr., Atmospheric pressure matrix-assisted laser desorption/ionization with analysis by ion mobility time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom. 2004, 18(8), 882—888. [Pg.69]