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As neuroprotective agent

Kemp JA, Kew JNC, Gill R (1999) NMDA receptor antagonists and their potential as neuroprotective agents, chapter 16 Ionotropic glutamate receptors in the CNS. Springer Verlag... [Pg.661]

Several glutamate antagonists have been or are in the process of being evaluated both preclinically and clinically as neuroprotective agents. For example, MK-801, an NMDA antagonist, reduces the detrimental effects of excess glutamate (as well as other insults to neurons) in a variety of animal models. Unfortunately the... [Pg.827]

Gill R, Kemp JA, Richards JG, Kew JNC (1999) NMDA receptor antagonists past disappointments and future prospects as neuroprotective agents. Curr Opin Cardiovasc Pulm Ren Invest Drugs 1 576-591... [Pg.290]

Hicks, D., Heidinger, V., Mohand-Said, S., Sahel, J., and Dreyfus, H. (1998). Growth factors and gangliosides as neuroprotective agents in excitotoxicity and ischemia. Gen. Pharmacol. 30, 265—273. [Pg.334]

Nitrone-Based Free Radical Traps as Neuroprotective Agents in Cerebral Ischemia and Other Pathologies... [Pg.438]

Preclinical Development of Neurosteroids as Neuroprotective Agents for the Treatment of Neurodegenerative Diseases... [Pg.442]

Fowler CJ (2003) Plant-derived, synthetic and endogenous cannabinoids as neuroprotective agents non-psychoactive cannabinoids, entourage compounds and inhibitors of N-acyl ethanolamine breakdown as therapeutic strategies to avoid psychotropic effects. Brain Res Rev 41 26-43... [Pg.42]

Micale N, Colleoni S, Postorino G et al (2008) Structure-activity study of 2, 3-benzodiaze-pin-4-ones noncompetitive AMPAR antagonists identification of the l-(4-amino-3-methyl-phenyl), 5-dihydro-7, 8-ethylenedioxy-4H-2, 3-benzodiaze pin-4-one as neuroprotective agent. Bioorg Med Chem 16 2200-2211... [Pg.136]

Biegon, A. (2004) Cannabinoids as neuroprotective agents in traumatic brain injury. Curr. Pharm. Design 10, 2177-2183. [Pg.105]

A new family of dibenzo[l,4,5]thiadiazepines 203 has been reported, which show promise as neuroprotective agents (14EJM350). A range of... [Pg.560]

Cornacchia C, Cacciatore I, Baldassarre L, Mol-lica A, Feliciani F, Pinnen F (2012) 2,5-Diketopi-perazines as neuroprotective agents. Mini Rev Med Chem 12 2-12... [Pg.391]

To understand fully the molecular basis for the in vivo effects of flavonoids and to assess comprehensively their potential as neuroprotective agents, further studies are needed, in particular with regard to metabolism, distribution across the blood-brain barrier, and neuropharmacological properties. [Pg.266]

Large family of novel imidazolyl nitrones synthesised and tested as neuroprotective agents. Many offer significant protection e.g. 80% protection) against a lethal dose of Bu OOH and readily penetrate the blood brain barrier. s... [Pg.62]

See other pages where As neuroprotective agent is mentioned: [Pg.1353]    [Pg.769]    [Pg.327]    [Pg.18]    [Pg.73]    [Pg.285]    [Pg.110]    [Pg.272]    [Pg.86]    [Pg.373]    [Pg.414]    [Pg.1353]    [Pg.354]    [Pg.277]    [Pg.73]    [Pg.596]    [Pg.193]    [Pg.291]    [Pg.632]    [Pg.1070]    [Pg.121]    [Pg.37]    [Pg.62]    [Pg.261]    [Pg.293]    [Pg.287]   
See also in sourсe #XX -- [ Pg.611 ]



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