Aryl hydrocarbon receptor signaling pathway

Miller CA 3rd. 1999. A human aryl hydrocarbon receptor signaling pathway constructed in yeast displays additive responses to ligand mixtures. Toxicol. Appl. Pharmacol. 160 297-303... [Pg.329]

Dibenzofuran induces hepatic, skin, and lung cytochrome P450 lAl, 1A2, and aryl hydrocarbon hydroxylase in rats. Thus, toxicity results from aryl hydrocarbon receptor signal transduction pathway. Bioactivation of many polycyclic hydrocarbon carcinogens is mediated by these enzymes. [Pg.792]

Sulentic, C., Holsapple, M., and Kaminski, N., Putative link between transcriptional regulation of IgM expression by TCDD and the aryl hydrocarbon receptor/dioxin-responsive enhancer signaling pathway, J. Pharmacol. Exper. Therapeut., 295, 705, 2000. [Pg.253]

Long WP, Pray-Grant M, Tsai JC, Perdew GH. 1998. Protein kinase C activity is required for aryl hydrocarbon receptor pathway-mediated signal transduction. Molec. Pharmacol. 53 691-700... [Pg.331]

Chan, W.K., G. Yao, Y.Z. Gu and C.A. Bradfield. Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways. Demonstration of competition and compensation. J. Biol. Chem. 274 12115-12123, 1999. [Pg.387]

Nie MH, Blankenship AL, Giesy JP. 2001. Interactions between aryl hydrocarbon receptor (AhR) and hypoxia signaling pathways. Envir Toxicol Pharmacol 10 17-27. [Pg.294]

Miao, W., Hu, L., Scrivens, P. J., and Batist, G. (2005) Transcriptional regulation of NF-E2 p45-related factor (NRF2) expression by the aryl hydrocarbon receptor-xenobiotic response element signaling pathway direct cross-talk between phase I and II drug-metabolizing enzymes../. Biol. Chem. 280, 20340-20348. [Pg.103]

Murphy KA, Quadro L, White LA (2007) The intersection between the aryl hydrocarbon receptor (AhR)- and retinoic acid-signaling pathways. Vitam Horm 75 33-67 Nebert DW, Dalton TP, Okey AB, Gonzalez FJ (2004) Role of aryl hydrocarbon receptor-mediated induction of the CYPl enzymes in environmental toxicity and cancer. J Biol Chem... [Pg.160]

Oesch-Bartlomowicz B, Huelster A, Wiss O, Anto-niou-Lipfert P, Dietrich C, Arand M, Weiss C, Bock-amp E, Oesch F (2005) Aryl hydrocarbon receptor activation by cAMP vs. dioxin divergent signaling pathway. Proc Natl Acad Sci U S A 102 9218-9223... [Pg.807]

Interaction with receptors (aryl hydrocarbon, estrogen, 67-kDa laminin, etc.) Modulation of signal transduction pathway (NrF2/keap 1, MEK/ERK, etc.) Antimutagenesis LOX inhibition... [Pg.300]

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