Applications of Chitosan

The major driving force in the development of new applications for chitosan lies in the fact that the polymer is biodegradable, biocompatible, and possesses specific adsorption properties. 

Attributing to the polycationic nature and several inherent properties, chitosan is currently receiving a great deal of interest as regards its applications in several diversified areas such as medical, food, textiles, water processing, cosmetics, agriculture, and paper [2], 

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In fact, one of the major applications of chitosan and some of its many derivatives is based on its ability to bind precious, heavy and toxic metal ions. Another article reviews the various classes of chitosan derivatives and compares their ion-binding abihties under varying conditions, as well as the analytical methods to analyze them, the sorption mechanism, and structural analysis of the metal complexes. Data are also presented exhaustively in tabular form with reference to each individual metal ion and the types of compounds that complex with it under various conditions, to help reach conclusions regarding the comparative efficacy of various classes of compounds [112]. 

Crini G, Badot PM (2008) Application of chitosan, a natural aminopolysaccharide, for dye removal from aqueous solutions by adsorption processes using batch studies a review of recent literature. Prog Polym Sci 33 399 447... 

This chapter focuses and reviews on the characteristics and biomedical application of chitosan and collagen from marine products and advantages and disadvantages of regeneration medicine. The understanding of the production processes of chitosan and collagen and the conformation of these biomaterials are indispensable for promoting the theoretical and practical availability. The initial inflammatory reactions associated with chitosan application to... 

Major applications of chitosan were previously focused on sludge dewatering, food processing, and metal ion chelation until the mid-1980s. Further, it has received considerable attention for its commercial applications in agriculture, chemistry, biomedical, food, cosmetic, and biotechnology industries (Alasalvar et ah, 2002 Knorr, 1984 Kurita,... 

Ueno, H., Mori, T., and Fujinaga, T. (2001). Topical formulations and wound healing applications of chitosan. Adv. Drug Deliv. Rev. 52,105-115. 

Dodane, V., and V.D. Vilivalam. 1998. Pharmaceutical applications of chitosan. Pharm Sci Technol Today 1 246. 

PEI grafting on chitosan is becoming a popular approach for modification of chitosan for gene delivery applications. In recent years several efforts to develop chitosan-g-PEI delivery vectors have been published. These include incorporation of mannose [117] and folic acid [118] derivatives for targeted delivery and application of chitosan-g-PEI for the delivery of siRNA [119]. 

No, H.K., Meyers, S.P., Prinyawiwatkul, W., Xu, Z. 2007. Applications of chitosan for improvement of quality and shelf life of foods A review. Journal of Food Science 72(5) R87-R100. 

TABLE 2.22 Comparison of the application of chitosan versus chitin... 

Suh, J.K.F. Matthew, H.W.T. Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering A review. Biomaterials 2000, 21, 2589-2598. 

Sanford PA (1989) Applications of Chitosan. In Skjak-Braek G, Anthonsen T, Sanford PA (eds) Chitin and Chitosan. Elsevier Applied Science, London, pp 51—69... 

Aspden, T., L. Blum and O. Skaugrud. 1997a. The effect of chronic nasal application of chitosan solutions on cilia beat frequency in guinea pigs. Ini. J. Pharm. 153 137-146. 

Cardenas, G., Orlando, P., and Edelio, T. 2001. Synthesis and applications of chitosan mercaptanes as heavy metal retention agent. Int. J. Biol. Macromol. 28, 167-174. 

Biopolymers Biomedical and Environmental Applications 6.10 Bio-medical Applications of Chitosan 6.10.1 Gene Therapy... 

Debasish Sahoo is a senior lecturer in the Institute of Nanobiotechnology, Cuttack, India. He has an MSc in Biotechnology and has carried out extensive research work on biomedical applications of chitosan. He recently submitted his PhD thesis to the faculty of Biotechnology, Utkal University. 

However, for most applications, practical use of chitosan has been limited by its physicochemical properties, in particular its low solubility above pH 6.5 and the pH-dependence of the ionic interactions in the formulations. Hence, chitosan derivatives have been recently developed to widen and improve the potential biomedical applications of chitosan. 

Application of Chitosan for Regeneration of Various Types of Tissue... 

Table 4 Application of chitosan scaffolds to liver tissue engineering... 

This review firstly focuses on modification of the chitosan molecule to obtain desired properties and functions. The most important material forms (porous scaffolds, hydrogels, and rods) and delivery vectors fabricated from chitosan and its derivatives will be introduced. Particularly, the interaction and modulation of stem cell behavior by chitosan will be discussed. Finally, the applications of chitosan-based materials for repair and regeneration of various tissues and organs such as skin, cartilage, and bone will be summarized. 

Production, Properties and Applications of Chitosan from Fungal Biomass.199... 

Therefore, the production of chitosan from fungal mycelia is gaining increasing interest for large scale production. Production, properties and applications of chitosan and glucan from fungal mycelia are presented in this chapter. 

The present volumes entitled Chitosan for Biomaterials 1 and 11 were conceived to provide broad and thorough knowledge for highly advanced applications of chitosan and its derivatives in the form of micro- and nanoparticles, nanocomposites, membranes, and scaffolds. The books consist of 15 chapters written in a manner that meets the expectations of scientists in various disciplines. 

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