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Antimicrobial agent, definition

Definitive therapy should be based on results of appropriately collected cultures and sensitivities, as well as clinical response to empiric antimicrobial agents. [Pg.524]

Most clinicians use a combination of oral antimicrobial agents and corticosteroids until there are definite signs of disease resolution. Decreasing inflammation with healing... [Pg.628]

Strictly, the definition should refer to substances that are antagonistic in dilute solution because it is necessary to exclude various common metabolic products such as alcohols and hydrogen peroxide. The term antibiotic is now commonly used for antimicrobial drugs in general, and it would be pedantic to object to this. Today, many commonly-used antibiotics are either fully synthetic or are produced by major chemical modification of naturally produced molecules hence, antimicrobial agent is perhaps a more accurate term, but antibiotic is much the commoner usage. [Pg.202]

Bacterial culture, identification of the causative pathogenic microorganism, susceptibility testing, definitive diagnosis, selection of the antimicrobial agent of choice, and... [Pg.230]

Response Surface Model A dose-response surface is an extension of dose-response lines (isobols) to three dimensions. In this representation there can be a dose-response surface representing additivity and surfaces above and below suggesting deviation from additivity. Tam et al. [90] studied the combined pharmacodynamic interactions of two antimicrobial agents, meropenem and tobramycin. Total bacterial density data, expressed as CFU (colony forming units), were modeled using a three-dimensional surface. Effect summation was used as the definition of additivity (null interaction hypothesis) and the pharmacodynamic model was assumedi to take the functional form... [Pg.52]

Oral antimicrobial agents sometimes have beneficial effects in inflammatory bowel disease. However, in the absence of any evidence pointing toward a definite microbial cause for the colitis in this patient, a drug that decreases inflammation is indicated. Sulfasalazine has significant anti-inflammatory action, and its oral use results in symptomatic improvement in 50-75% of patients. The drug is also used for its anti-inflammatory effects in rheumatoid arthritis. The answer is (D). [Pg.409]

The determination of MIC of antibiotics was performed by microtiter method. Antimicrobial agents were diluted by serial dilutions MPB in flat-bottomed plates, they were also added to the culture of Staphylococcus aureus, and were incubated for 24 hr at 34°C. The control was culture Staphylococcus aureus without antimicrobial agents. After that mixture sowed on solid nutrient medium Mueller-Hinton agar for calculation of amount of colony forming particles and MIC definitions. The MIC was considered to be the lowest concentration, which retards the growth of Staphylococcus aureus during the incubation period. [Pg.135]

As a result of mild heat treatment, drying, or chemical antimicrobial treatment, cells may be sublethally injured. A cell is, by definition, sublethally injured if it is unable to grow on a selective medium that is typically suitable for normal healthy cells of that type. Sublethally injured cells may recover when transferred to a suitable non-selective medium and thus regain all their normal characteristics, including resistance to selective antimicrobial agents and pathogenicity. This recovery process is called resuscitation. [Pg.400]

In processed foods, benzoic and its salts are used up to a level of 0.1%. The effectiveness of these preservatives increases with decreasing pH. The composition of the food therefore has an effect on their efficiency and suitability for use. This is because the ratio of undissociated (i.e., free) benzoic acid to ionized benzoic acid increases as the pH decreases. It is generally accepted that the undissociated benzoic acid is the active antimicrobial agent. Although no definitive theory has been yet proposed to explain this antimicrobial effects, it is believed to be related to the high lipid solubility of the undissociated benzoic acid, which allows it to accumulate on the cell membranes or on various structures and surfaces of the bacterial cell, effectively inhibiting its cellular activity. [Pg.171]

Staphylococcus aureus without antimicrobial agents. After that mixture sowed on solid nutrient medium Mueller-Hinton agar for calculation of amount of colony forming particles and MIC definitions. MIC was considered to be the lowest concentration, which retards the growth of Staphylococcus aureus during the incubation period. [Pg.396]

EUCAST (2000), Terminology relating to methods for the determination of snscepti-bility of bacteria to antimicrobial agents , European Committee on Antimicrobial Susceptibility Testing Definitive document E.Def 1.2 May 2000 http //www.srga. org/Eucastwt/eucastdefinitions.htm. [Pg.186]

Vopak USA http //www.vopakusa.com-, Westco http //www.westcochemicais.com Ammonium phenolsulfonate CAS 61886-53-1 EINECS/ELINCS 263-293-6 Synonyms Ammonium hydroxybenzenesulfonate Ammonium sulfocarbolate Benzenesulfonic acid, hydroxy-, monoammonium salt Hydroxybenzenesulfonic acid, monoammonium salt Monoammonium hydroxybenzenesulfonate Definition Ammonium sait of phenoisuifonic acid Empihcai C6H6O4S H N Properties M.w. 573.62 Uses Antimicrobial, deodorant agent in cosmetics... [Pg.274]

Definition Extract derived from Cinchona spp. Uses Natural flavoring agent in foods medicine (analgesic, anesthetic, antibacterial, antimalarial, antimicrobial, antipyretic, astringent, bactericide, fungicide, febrifuge. [Pg.950]

Uses Antimicrobial in cosmetics intermediate for epoxies, urethane resins, and antistatic lubricants for the textiles and plastics crosslinking agent for high-temp, resist, polyester or imide-amide wire enamels, acrylic, PU spec, coatings lubricant film-former DEDM hydantoin dilaurate Synonyms Diethylol dimethyl hydantoin dilaurate Di-(2-hydroxyethyl) dimethylhydantoin dilaurate Di-(2-hydroxyethyl)-5,5-dimethyl hydantoin dilaurate 2,4-lmidazolidinedione, 1,3-bis (2-decanoyloxyethyl)-5,5-dimethyl-Definition Diester of DEDM hydantoin Empirical C29H60N2O6 Properties M.w. 532.80... [Pg.1182]

Synonyms Citrus aurantium dulcis wax Orange peel wax Orange wax Definition Wax obtained from the peei of the orange, Citrus aurantium dulcis Uses Emollient, moisturizer, UV-A and -B absorber, natural antioxidant, mild antimicrobial, fragrance, dispersant, wetting agent in cosmetics, sun care, makeup, shampoos, pharmaceuticals antiinflammatory, analgesic (on bums) solubilizer water resist, aid... [Pg.2999]


See other pages where Antimicrobial agent, definition is mentioned: [Pg.91]    [Pg.776]    [Pg.769]    [Pg.13]    [Pg.709]    [Pg.123]    [Pg.824]    [Pg.305]    [Pg.328]    [Pg.176]    [Pg.245]    [Pg.173]    [Pg.117]    [Pg.184]    [Pg.54]    [Pg.69]    [Pg.16]    [Pg.58]    [Pg.358]    [Pg.70]    [Pg.1544]    [Pg.3040]    [Pg.208]    [Pg.322]   
See also in sourсe #XX -- [ Pg.3 ]




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