Antimicrobial activity against Candida albicans

Pyridoxatin was 20 times as active (IC50 = 0.55 pg/ml) as vitamin E as an inhibitor of free radical induced lipid peroxidation in rat liver microsomes [221]. It inhibited (IC50= 1-95 Ug/ml) hemolysis of rat erythrocytes catalyzed by a free radical initiator [221]. Pyridoxatin inhibited the growth of HeLa cells (IC50 = 1.0 pg/ml), but only displayed antimicrobial activity against Candida albicans (MIC = 1.64 pg/ml) [221]. 

Capric acid (C10 0) and lauric acid (C12 0) have antimicrobial activity against Candida albicans strains (Bergsson et al., 2001). 

The least toxic, insofar as mammals are concerned, is the simplest structure of all, trichodermin, isolated from Trichoderma viride. It is, nevertheless, inhibitory to etiolated wheat coleoptiles down to 10 5M. The LD50 is 1 g/Kg orally, and 0.5-1 g/Kg subcutaneously in mice, and its low toxicity did, at one time, make it a potential candidate as a pharmaceutical antimicrobial by Leo Pharmaceuticals. It was an effective bacteriocide and, also, exhibited good activity against Candida albicans,16 From the perspective of activity on whole plant growth, it is a... 

The essential oil from another Achillea species, Achillea sintenisii, was assayed for its antimicrobial activities against 12 bacteria and 2 yeasts [26]. The oil was found to be active against some of the test microorganisms studied. The analysis of the oil revealed that the main components, e.g., camphor. Fig. (1) and eucalyptol, possessed appreciable activity against Candida albicans and Clostridium perfringens. The antimicrobial activities of the essential oils of Achillea setacea W. K. and Achillea teretifolia Willd. were individually evaluated against 14... 

Some empirical uses of S. sclarea suggest that its essential oil, like many essential oils of the Lamiaceae family, has an inhibitory effect on microorganisms pathogenic to man. Ulubelen et al. [51] examined the antimicrobial activity of some diterpenes and sesquiterpenes found in an acetone extract of S. sclarea. They found that 2, 3-dehydrosalvipisone, sclareol, manool, 7-oxoroyleanone, spathulenol and caryophyllene oxide were active against Staphylococcus aureus 2, 3- dehydrosalvipisone and manool were active against Candida albicans and caryophyllene oxide was active against Proteus mirabilis. 

Arylisatogens show significant antimicrobial activity against bacteria,31 mycoplasma organisms, and the mold Candida albicans.19 No useful biological activity has been observed with indolones.49... 

Chen, H.-L., Yen, C.-C., Lu, C.-Y., Yu, C.-H., and Chen, C.-M. (2006) Synthetic porcine lactoferricin with a 20 residue peptide exhibits antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans. J. Agric. Food Chem. 54, 3277-3282. 

Among the 60 constituents of the cumin oil identified by GC, GC-MS and olfactometry as essential volatiles, cuminaldehyde (36%), /3-pinene (19.3%), p-cymene (18.4%) and y-terpinene (15.3%) are the principal components showing high antimicrobial activity against the mould A. niger, the Gram-positive bacteria, Bacillus subtilis and S. epidermidis, as well as the yeasts, Saccharomyces cerevisiae and Candida albicans (Jirovetz et al., 2005). 

Holetz et al. [38] reported the antimicrobial screening of some plants used in the Brazilian folk medicine for the treatment of infectious diseases. Two members of the Anthemideae tribe, Tanacetum vulgare L. and Arctium lappa L. presented some degree of antimicrobial activity against Staphylococcus aureus, Escherichia coli and Candida albicans. 

The essential oil composition and antimicrobial activity of Osmitopsis asteriscoides (Berg) Less, a medicinal plant used in traditional preparations in South Africa has been investigated [125]. Three different antimicrobial methods were comparatively evaluated against Candida albicans. Staphylococcus aureus and Pseudomonas aeruginosa The two major essential oil components, camphor. Fig. (1) and 1,8-cineole, Fig. (2) were investigated, indieating the positive antimicrobial efficacy of 1,8-cineole, Fig. (2), independently and in combination with camphor, Fig. (1). 

The methanol extract of the campsite plant Xanthium strumarium (Cocklebur) displayed antimicrobial activity against Proteus vulgaris. Staphylococcus aureus. Bacillus subtilis, Candida albicans and Candida pseudotropicalis [170]. This activity was attributable to the presence of the sesquiterpene xanthanol. 

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