Antibodies nature

Kwong PD, Wyatt R, Robinson J, Sweet RW, Sodroski J, Hendrickson WA (1998) Structure of an HIV gpl20 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody. Nature 393 648-659... 

A second type of occultation concerns the relations that exist between biomolecules. In the same way that the antibody nature of an immunoglobulin molecule becomes evident only when its complementary antigen has been recognized, the epitope nature of a set of amino acids in a protein can... 

Nl. Nagata, S., Tsutsumi, T., Yoshida, R, and Ueno, Y, A new type sandwich immunoassay for microcystin Production of monoclonal antibodies specific to the immune complex formed by microcystin and an anti-microcystin monoclonal antibody. Natural Toxins 1, 49-55 (1999). 

Boulianne GL, Hozumi N, Shulman MJ. 1984. Production of functional chimeric mouse/human antibody. Nature. 312 643-646. 

Taylor, R.B., Duffus, W.P.H., Raff, M.C., de Petris, S. (1971). Redistribution and pinocystosis of lymphocyte surface immunoglobulin molecules induced by anti-immunoglobulin antibody. Nature New Biol. 233, 225-229. 

Weigert, M.G., Cesari, I.M., Yonkovich, S.J., Cohn, M. (1970). Variability in the lambda light chain sequences of mouse antibody. Nature 228, 1045-1047. 

Lee, S. and Sullenger, B. (1997) Isolation of a nuclease resistant decoy RNA that can protect human acetylcholine receptors from myasthenic antibodies. Nature, 15, 41 15. 

Shulman M, Wilde CD, Kohler G (1978), A better cell line for making hybridomas secreting specific antibodies, Nature 276 269-270. 

Dll. Dresser, D. W., Most IgM producing cells in the mouse secrete auto-antibodies. Nature (London) 274, 480-483 (1978). 

Bizebard, T., Gigant, B., Rigolet, P., Rasmussen, B., Diat, O., Bosecke, P., Wharton, S. A., Skehel, J. J., and Knossow, M. (1995). Structure of influenza virus haemagglutinin complexed with a neutralizing antibody. Nature 376, 92-94. 

Ulrich HD, Mundorff E, Santarsiero BD, Driggers EM, Stevens 113. RC, Schultz PG. The interplay between binding energy and catalysis in the evolution of a catalytic antibody. Nature 1997 389(6648) 271-275. 

Steinitz, M., Klem, G., Koskimies, S., and Makel, O. (1977) EB virus-induced B lymphocyte cell lines producing specific antibody. Nature 269, 420. 

Kartner, N. Evernden-Porelle, D. Bradley, G. Ling, V. Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies. Nature 1985, 316,... 

Immunization is either passive or active. In passive immunization, biotech-nologically constructed antibodies are raised as in animals the same as for antibody-based diagnostics, and then injected into human beings. This procedure is expensive and so is limited to life-threatening situations when the infected patient has not enough time to produce his or her own antibodies naturally. Ideally the antibodies must be humanized by protein engineering, namely made to look human, or else they are likely to be attacked by the body as alien animal products. 

Schoch P, Richards JG, Haring P, Takacs B, Stahli C, Staehelin T, Haefely W, Mbhler H (1985) Colocalization of GABA, receptors and benzodiazepine receptors in the brain shown by monoclonal antibodies. Nature, 314, 168-171. 

Cloned Cows Generate Human Antibodies. Nature Biotechnol., 2002 10 1038. 

M5. Miller, H., and Owen, G., Immuno-electrophoresis of insulin-binding antibodies. Nature 188, 67 (1960). 

Immunogenicity Natural antibodies Naturally occurring Hennig et al. 

Shuhnan, M., WUde, C.D., and Kohler, G., A hetter cell hue for making hyhridomas secreting specific antibodies. Nature, 276, 269, 1978. 

Keilhauer, R., Faissner, A. and Sehachner, M. (1985) Differential inhibition of neuron-neuron, neuron-astrocyte and astrocyte-astrocyte adhesion by LI, L2 and N-CAM antibodies. Nature 316 728-730. 

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