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Annulus fibrosus

Fig. 2 Representative histological images of (a) bovine annulus fibrosus (H E staining), (b) bovine nucleus pulposus (H E staining), and (c) porcine notochordal cells (Alcian blue staining for GAGs with fast red nuclei stain)... Fig. 2 Representative histological images of (a) bovine annulus fibrosus (H E staining), (b) bovine nucleus pulposus (H E staining), and (c) porcine notochordal cells (Alcian blue staining for GAGs with fast red nuclei stain)...
S. Inerot and I. Axelsson, Structure and composition of proteoglycans from humans annulus fibrosus. Connect. Tissue Res., 26 (1991) 47 -63. [Pg.261]

Nachemson, A., Lewin, T., Maroudas, A. and Freeman, M.A. (1970) In vitro diffusion of dye through the end-plates and the annulus fibrosus of human lumbar inter-vertebral discs. Acta Orthop Scand 41, 589-607... [Pg.200]

Nerurkar NL, Elliott DM, Mauck RL (2007) Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering. J Orthop Res 25(8) 1018-1028... [Pg.211]

Figure 1 The intervertebral disk. A normal young adult human disk is shown with an outer lamellar annulus fibrosus and an inner gelatinous nucleus pulposus. Figure 1 The intervertebral disk. A normal young adult human disk is shown with an outer lamellar annulus fibrosus and an inner gelatinous nucleus pulposus.
Wang et al [35] have been compared the regenerative potentials of the AF, NF and CEF-derived stem cells with that of the classic BMSCs in a rabbit disc degeneration model. They found cartilage endplate-derived stem cells (CESCs) with superior capacity compared with the annulus fibrosus-derived stem cells (AFSCs), nucleus pulposus-derived stem cells (NFSCs), and BM-MSCs (p<0.05). This information provides good direction for the application of disc-derived stem cells. [Pg.432]

Sharifi, S., Bulstra, S.K., Grijpma, D.W., Kuijer, R. Treatment of the degenerated intervertebral disc closure, repair and regeneration of the annulus fibrosus. J. Tissue Eng. Regen. Med. (2014) doi 10.1002/term.l866... [Pg.440]

Hee HT, Zhang J, Wong HK (2010) Effects of cyclic dynamic tensile strain on previously compressed inner annulus fibrosus and nucleus pulposus cells of human intervertebral disc - an in vitro study. J Orthop Res 28(4) 503-509... [Pg.368]

PLLA G-CSF Direct incorporation regeneration of damaged annulus fibrosus Scaffolds for reconstitution of skin and wound healing [41]... [Pg.179]

Driscoll, T.P., Nakasone, R.H., Szczesny, S.E., Elliott, D.M., and Mauck, R.L. (2013) Biaxial mechanics and inter-lamellar shearing of stem-cell seeded electrospun angle-ply laminates for annulus fibrosus tissue engineering. / Orthop. Res., 31 (6), 864-870. [Pg.183]

M. et al. (2012) Bioactive electrospun scaffold for annulus fibrosus repair and regeneration. Eur. Spine J., 21 (Suppl 1), S20-S26. [Pg.190]

Future research efforts in IVD arthroplasty should focus on either partial or full disc functional restoration. This may include NP implants and/or reinforcement or total disc replacement. PVA-C, as a hydrogel, has many interesting properties, such as its long-term biocompatibility and nontoxicity. It is also strongly hydrophilic and viscoelastic with nonlinear stress-strain characteristics similar to the IVD. It has a very low coefficient of friction and has good wear resistance [23]. However, its strength is still too low to serve as a practical functional replacement of the annulus fibrosus. PVA-BC may further increase the strength of the PVA-C to make it a viable candidate material for IVD fabrication. [Pg.307]

Perie D, MacLean J, Owen J, latridis J (2006) Correlating material properties with tissue composition in enzymatically digested bovine annulus fibrosus and nucleus pulposus tissue. Ann Biomed Eng 34 769-777... [Pg.320]

The intervertebral disc contains two distinct regions, the nucleus pulpo-sus and the annulus fibrosus. The nucleus occupies about 50% of the volume of the disc, and contains mostly water and small amounts of randomly oriented collagen fibers, cells and non-collagenous proteins [19]. The annulus is a tough ring-like structure that surrounds the nucleus. Highly oriented collagen fibers (primarily Types I and II) form a laminate structure in the annulus, with approximately 20-25 laminae oriented alternately at... [Pg.49]

Annulus Fibrosus 85 (innermost layer) 5 (innermost layer)... [Pg.50]

Marchand, F. and Ahmed, A.M. (1988) Investigation of the laminate structure of lumbar disc annulus fibrosus. Trans. Orthop. Res. Soc., 13, 271. [Pg.57]

Best B.A., Guilak, F., Setton, L.A., Zhu, W., Saed-Nejad, F., Ratcliffe, A., Weidenbaum, M. and Mow, V.C. (1994) Compressive mechanical properties of the human annulus fibrosus and their relationship to biochemical composition. Spine, 19, 212-221. [Pg.57]

Gower, W.E. and Pedrini, V. (1969) Age-related variations in protein-polysaccharide from human nucleus pulposus, annulus fibrosus and costal cartilage. J. Bone Joint Surg., 51A, 1154-1162. [Pg.57]

Galante, J.O. (1967) Tensile properties of the human lumbar annulus fibrosus. Acta Orthop. Scand., (Suppl. 100), 1-91. [Pg.57]

Therefore, the high compression loads at L5-S1 are borne primarily by the nucleus pulposus of the disc and the central end plate of the vertebral body. The high shear loads at L5-S1 are borne principally by peripheral structures, specifically the articular facets and the annulus fibrosus of the disc. [Pg.57]

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