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Scaffolds electrospun

Early reports on electrospun scaffolds described poor cellular infiltration [175], Frequently, cells adhered at the surface and thus coated the nano- or submicrometer-scaled electrospun meshes due to the small pore size. In order to overcome this limitation, pore sizes were increased by combining ES with other methods. These approaches included the coating of microfibers with nanofibers [183], Other strategies combine ES with leaching [184, 185], freeze-drying [186], blowing agents [187], or ice templates [188],... [Pg.182]

Others have combined electrospun scaffolds with scaffolds created by other techniques to create a 3D bone-1 ike scaffold for bone regeneration. For instance, Martins et al. [62] combined both electrospinning and rapid prototyping in order to create a 3D bone-like structure. This method is very similar to the layer-by-layer... [Pg.92]

Ekaputra AK et al (2009) Composite electrospun scaffolds for engineering tubular bone grafts. Tissue Eng A 15(12) 3779—3788... [Pg.124]

Wolfe PS, Sell SA, Bowlin GL (2011) Regenerative potential of electrospun scaffolds incorporated with platelet rich plasma. In Proceedings 15th Annual Hilton Head Workshop on regenerative medicine, Hilton Head Island... [Pg.125]

Baker BM et al (2008) The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers. Biomaterials 29(15) 2348-2358... [Pg.130]

Rubenstein D et al (2007) Bioassay chamber for angiogenesis with perfused explanted arteries and electrospun scaffolding. Microcirculation 14(7) 723-737... [Pg.209]

Based on these ideas, the concept of a dual drug scaffold wound dressing was put forward. Such a scaffold would offer a unique combination of the inherent properties of electrospun scaffolds such as promoting cell proliferation and simultaneously providing anesthetic and antibiotic activity for pain relief and healing. ... [Pg.1321]

FIGURE 12.8 SEM of electrospun scaffold using LTU polymer loaded with a plasmid DNA and linear polyethyleneimine complex. [Pg.215]

Ekaputra AK, Prestwich GD, Cool SM, Hutmacher DW (2008) Combining electrospun scaffolds with electrosprayed hydrogels leads to three-dimensional cellularization of hybrid constructs. Biomacromolecules 9 2097-2103... [Pg.200]

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Electrospun

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