Andrographis paniculata

Andrographolide, a labdane-diterpenoid lactone, is the principal bioactive chemical constituent of Andrographis paniculata (Brum. F.) Nees (family Acanthaceae) this prime constituent is mainly concentrated in leaves and can easily be isolated from the crude plant extracts as crystalline... [Pg.335]

Rajani M, Shrivastava N, Ravishankara MN. (2000) A rapid method for isolation of andrographolide from Andrographis paniculata Nees (kahnegh). Pharm Biol 38 204-209. [Pg.358]

Knlyal P, Tiwari UK, Shukla A, Gaur AK. (2010) Chemical constituents isolated from Andrographis paniculata. Indian J Chem 49B 356-359. [Pg.358]

Sabn KK, Padmesh P, Seeni S. (2000) Intraspecific variation in active principle content and isozymes of Andrographis paniculata Nees (Kahnegh) A traditional hepatoprotective medicinal herb. J Med Arom Plant Sci 23 637-647. [Pg.358]

Rao NK. (2006) Anti-hyperglycemic and renal protective activities of Andrographis paniculata roots chloroform extract. Iran J Pharmacol Ther 5 47-50. [Pg.358]

Patarapanich C, Laungcholatan S, Mahaverawat N, Chaichantipayuth C, Pummangura S. (2007) HPLC determination of active diterpene lactones from Andrographis paniculata Nees planted in various seasons and regions in Thailand. Thai J Pharm Sci 31 91-99. [Pg.359]

Mishra SK, Sangwan NS, Sangwan RS. (2007) Andrographis paniculata (Kalmegh) A review. Pharmacog Rev 1 283-298. [Pg.359]

Jarukamjom K, Nemoto N. (2008) Pharmacological aspects of Andrographis paniculata on health and its major diterpenoid constituent andrographolide. J Health Sci 54 370-381. [Pg.359]

Niranjan A, Tiwari SK, Lehri A. (2010) Biological activities of Kalmegh (Andrographis paniculata Nees) and its active principles — a review. Indian J Nat Prod Res 1 125-135. [Pg.359]

Rao YK, Vimalamma G, Rao CV, Tzeng Y. (2004) Flavonoids and andrographolides from Andrographis paniculata. Phytochemistry 65 2317-2321. [Pg.359]

Li W, Xu X, Zhang H, Ma C, Fong H, Van Breemen R, Fitzloff J. (2007) Secondary metabolites from Andrographis paniculata. Chem Pharm Bull 55 455 58. [Pg.359]

Sheeja K, Shihab PK, Kuttan G. (2006) Antioxidant and anti-inflammatory activities of the plant Andrographis paniculata Nees. Immunopharmacol Immunotoxicol 28 129-140. [Pg.360]

Chandrasekaran CV, Gupta A, Agarwal A. (2010) Effect of an extract of Andrographis paniculata leaves on inflammatory and allergic mediators in vitro. J Ethnopharmacol 129 203-207. [Pg.360]

Chao WW, Kuo YH, Lin BE (2010) Anti-inflammatory activity of new compounds from Andrographis paniculata by NE-kB transactivation inhibition. J Agric Eood Chem 58 2505-2512. [Pg.360]

Akowuah GA, Zharik 1, Mariam A. (2008) Analysis of urinary andro-graphohdes and antioxidant status after oral administration of Andrographis paniculata leaf extract in rats. Eood Chem Toxicol 46 3616-3620. [Pg.360]

Lin FL, Wu SJ, Lee SC, Ng LT. (2009) Antioxidant, antioedema and analgesic activities of Andrographis paniculata extracts and their active constitnent andrographolide. Phytother Res 23 958-964. [Pg.361]

Andrographolide, a potential cancer therapentic agent isolated from Andrographis paniculata.. J Exp Ther Oncol 3 147-158. [Pg.361]

Handa SS, Sharma A. (1990) Hepatoprotective activity of andrographolide from Andrographis paniculata against carbon tetrachloride. Indian J Med Res 92 276-283. [Pg.361]

Koul IB, Kapil A. (1994) Effect of diterpenes from Andrographis paniculata on antioxidant defense system and lipid peroxidation. Indian J Pharmacol 26 296-300. [Pg.362]

Amroyan E, Gabrielian E, Panossian A, Wikman G, Wagner H. (1999) Inhibitory effect of andrographolide from Andrographis paniculata on PAF-induced platelet aggregation. Phytomedicine 6 27-31. [Pg.362]

Maiti K, Gantait A, Mukherjee K, Saha BP, Mukheijee PK. (2006) Therapeutic potentials of andrographolide from Andrographis paniculata A review. J Nat Remed 6 1-13. [Pg.362]

Zhao E, He EQ, Wang L, Liu K. (2008) Anti-tumor activities of andrographolide, a diterpene from Andrographis paniculata, by inducing apoptosis and inhibiting VEGF level. J Asian Nat Prod Res 10 413-419. [Pg.362]

Raina AP, Kumar A, Pareek SK. (2007) HPTLC analysis of hepatoprotec-tive diterpenoid andrographolide from Andrographis paniculata Nees (Kalmegh). IndJPharm Sci 69 473 75. [Pg.362]

Chakravarti RN, Chakravarti D. (1951) Andrographolide, the active constituent of Andrographis paniculata Nees a preliminary communication Indian Med Gaz 86 96-97. [Pg.363]

Choudhury RB, Poddar MK. (1984) Andrographolide and Kahnegh (Andrographis paniculata) extract In vivo and in vitro effect on hepatic lipid peroxidation. Methods Find Exp Clin Pharmacol 6 481. [Pg.363]

Choudhury RB, Haque SJ, Poddar MK. (1987) In vitro and in vivo effects of kalmegh (Andrographis paniculata) extract and andrographolide on hepatic microsomal drug metabolising enzymes. Planta Med 53 135-140. [Pg.363]

Kapil A, Koul IB, Banerjee SK, Gupta BD. (1993) Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata. Biochem Pharmacol 46 182-185. [Pg.363]

Pekthong D, Martin H, Abadie C, Bonet A, Heyd B, Mantion G, richert L. (2008) Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and andrographolide. J Ethonopharmacol 115 432-440. [Pg.363]

Siripong P, Konkathip B, Preechanukool K, Picha P, Tunsuwan K, Taylor WC. (1992) Cytotoxic diterpenoid constituents from Andrographis paniculata Nees. leaves. J Sci Soc Thai 18 187-194. [Pg.365]

Geethangili M, Rao YK, Fang SH, Tzeng YM. (2008) Cytotoxic constituents from Andrographis paniculata induce cell cycle arrest in Jurkat ceBs,. Phytother Res 22 1336-1341. [Pg.365]

Puri A, Saxena R, Saxena RP, Saxena KC, Srivastava V, Tandon IS. (1993) Immunostimulant agents from Andrographis paniculata. J Nat Prod 56 995-999. [Pg.366]

Kumar RA, Sridevi K, Kumar NV, Nanduri S, Rajagopal S. (2004) Anticancer and immunostimulatory compounds from Andrographis paniculata. J Ethanopharmacol 92 291-295. [Pg.366]

Sheeja K, Kuttan G. (2007) Activation of cytotoxic T lymphocyte responses and attenuation of tumor growth in vivo by Andrographis paniculata extract and andrographolide. Immunopharmacol Immunotoxicol 29 81-93. [Pg.366]

Reddy VL, Reddy SM, Ravikanth V, Krishnaiah P, Goud TV, Rao TP, Ram TS, Gonnade RG Bhadbhade M, Venkateswarlu Y. (2005) A new bis-andrographolide ether from Andrographis paniculata Nees and evaluation of anti-HIV activity. Nat Prod Res 19 223-230. [Pg.367]

Inhibition of proprotein converases-1,-7 and furin by diterpenes of Andrographis paniculata and their succinoyl esters. Biochem J 338 107-113. [Pg.367]

Thisoda P, Rangkadilok N, Pholphana N, Worasuttayangkum L, Ruchirawat S, Satayavivad 1. (2006) Inhibitory effect of Andrographis paniculata extract and its active diterpenoids on platelet aggregation. Eur J Pharmacol 553 39 5. [Pg.367]

Pharmacokinetic and oral bioavailabiUty of andrographolide from Andrographis paniculata fixed combination Kan Jang in rats and human. Phytomedicine 7 351-364. [Pg.367]

Wangboonskul J, Daodee S, Jarukamjom K, Sripanidkulchai B. (2006) Pharmacokinetic smdy of Andrographis paniculata tablets in healthy Thai male volunteers. Thai Pharm Health Sci J 1 209-218. [Pg.367]

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