Analytical service programs

The valuable discussions and technical assistance of Drs. Jon W. Belisle, Research Analytical Services, David L. June, Riker Analytical, and James R. Throckmorton, Agricultural Products Division of 3M, are gratefully acknowledged. I am also indebted to Dr. Frank H. Clarke of the Ciba-Geigy Corporation for an advance copy of his Apple program and helpful discussions. 

For a site activity under the purview of the Removal Program, the On-Scene Coordinator (OSC) has the responsibility of preparing the site-specific Sampling QA/QC Plan. The objective of the Sampling QA/QC Plan is to ensure that field sampling efforts and analytical services will provide data of known quality [The quality of data are known when all components associated with their derivation are 0097—6156/90/0431—0082 06.00/0 1990 American Chemical Society... 

The field data QA/QC samples consisted of duplicate samples, field spikes with NIST (National Institute of Standards and Technology) traceable spike standards, field blanks, and breakthrough sections. Frontier Global Sciences (FGS), the project laboratory, provided all analytical services as well as all sampling media including spiked sorbent trap. FGS is a NELAP (National Environmental Laboratory Accreditation Program) accredited and ISO 17025 accredited laboratory specializing in the analysis of trace and heavy metals. 

Method 6020-CLP-M under the Contract Laboratory Program is available as a Special Analytical Services (SAS) method. 

The U S EPA Contract Laboratory Program (CLP) is a national network of EPA personnel, commercial laboratories and support contractors. The CLP supports the EPA s Superfund program, created under the 1980 Comprehensive Environmental Response, Corqtensation, and Liability Act (CERCLA), and currently under the 1986 Superfund Amendments and Reauthorization Act (SARA). The CLP s primary service is the provision of anal34ical data of known and documented quality, through its routine analytical services, to its customers. All analytical services are performed by EPA-approved contract laboratories that must meet stringent requirements and standards in order to be a part of the CLP. 

Providing and supporting infrastructure (analytical and computer services) Locating useful information without intimate knowledge of the language Program... 

Services - including programs for spectra processing and editing, manipulation with different types of data like samples compositions, terms of determination, analytical lines intensities. 

QA requires the efficient analysis of many samples to support routine production release and stability programs. Methods are typically established in the analytical development group. Efficiency and convenience issues, including the speed of media preparation and the relative convenience of data handling and documentation, are important here. While compliance is important in all aspects of the pharmaceutical industry, QA functions must approach compliance perfection. Depending upon the facility, the automated apparatus may be tailored to specific methods with fixed configurations. Dissolution methods may be routine enough that a custom system, optimized for productivity, may be justified. Compliance of USP and use of industry standard apparatus is important to maintain compatibility with other company laboratories or in the case contract laboratory services are required. 

Pricing of cooling water programs by water treatment vendors will almost always take into account the amount of service time expected to be spent on-site during the life of the contract or for each fiscal year for routine analytical inspection and advisory work. 

The authors are grateful to the International Programs in Chemical Sciences (1PICS) for fostering intra-African cooperation under the auspices of the Network for Analytical and Bioassay Services in Africa (NABSA). B.M.A. acknowledges financial support from the University of Botswana administered by the Faculty Research and Publication Committee. 

The Technical Services function of AOCS establishes, revises, and annually updates AOCS Methods, the Official Methods and Recommenced Practices of the American Oil Chemists Society22 for fats, oils, and soap technology Spanish AOCS Methods, a Spanish translation of the more commonly used AOCS Methods and Physical and Chemical Characteristics of Oils, Fats and Waxes. Leaders of the methods development committees coordinate closely with AOAC International (formerly the Association of Official Analytical Chemists). AOCS Methods are recognized as Official Methods in US FDA activities and when litigation becomes necessary in industry trade. Additionally, the Technical Services function operates a Laboratory Proficiency Program (formerly the Smalley Check Sample Program) and oversees distribution and statistical analysis of 30 different series of basic laboratory quality assur-ance/quality control test samples. Certification as AOCS Approved Chemists, or as AOCS... 

The California Department of Food and Agriculture is testing immunochemical assays for possible adept ion as analytical methods for pesticide residues in environmental samples. The work was initially undertaken by the Environmental Monitoring and Pest Management Branch (EM PM), and now involves the Department s Chemistry Laboratory Services Brandi as well. This paper discusses the history of our involvement in irrmunochemistry as an analytical method, our imnunochemical method development program, the format and other details of the assay we are using, and finally, looks into the future in anticipation of sane institutional problems which may arise. 

USDA Food Safety and Inspection Service Compound Evaluation and Analytical Capability National Residue Program Plan. Brown, J., Ed. USDA FSIS Science Program, Wash. D.C., 1987. p. 4.13... 

The selection and evaluation of analytical methods are discussed in Chapters 14 and 15. It is important to recognize, however, that the initial evaluation of a method often takes place in a setting somewhat more idealized than the production setting. It is therefore desirable to have a start-up period in the service laboratory before test results are to be reported. This period allows tune to (1) discover any additional problems, (2) develop maintenance programs that alleviate those problems, and (3) train a sufficient number of analysts to support the routine service operation. 

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