Amniotic fluid-derived stem cells

Skardal, A., Mack, D., Kapetanovic, E., Atala, A., Jackson, J.D., Yoo, J., Soker, S., 2012. Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds. Stem Cells Transl. Med. 1, 792-802. 

Human amniotic fluid-derived stem cells... 

AFSCs Amniotic fluid-derived stem cells 7.7.6... 

Placental membranes and amniotic fluid are also a rich source of stem ceUs. The placental membranes and amniotic fluid stem cells that support fetal development have seen an inaease in scientific publication recently as a result of research into their notable regeneration potential. These stem cells have the capacity to differentiate into multiple tissue types, whieh holds promise for a range of clinical applications. Several scientific journal articles that collectively outline the biological characteristics and therapeutic potential of amniotic fluid and placental membrane-derived stem cells are referenced at the conclusion of this chapter. 

Trachea TE has been one of the most promising approaches to providing a potential clinical application for the treatment of long-segment tracheal stenosis. The sources of the cells are particularly important as the primary factor for TE. Besides autologous mature cells, various stem cells, including bone marrow-derived mesenchymal stem cells (MSCs), adipose tissue—derived stem cells, umbilical cord blood—derived mesenchymal stem cells, amniotic fluid stem cells, embryonic stem cells, and induced pluripotent stem cells, have received extensive attention in trachea TE [118]. 

Induced pluripotent stem cells are the adult cells that have been transformed into pluripotent stem cells through programming. Among adult stem cells, Mesenchymal stem cell is widely used as a multipotent source. Mesenchymal stem cell is derived from bone marrow stroma and can differentiate into a variety of cell types in vitro. Other sources of adult stem cells include the amniotic fluid and placental derived stem cells [29, 30]. 

Cananzi M, Atala A, et al. Stem cells derived from amniotic fluid new potentials in regenerative medicine. Reprod Biomed Online 2009 18(Suppl. l) 17-27. 

De Coppi, R, A. CaUegari, A. Chiavegato et al. 2007b. Amniotic fluid and bone marrow derived mesenchymal stem cells can be converted to smooth muscle cells in the cryo-injured rat bladder and prevent compensatory hypertrophy of surviving smooth muscle cells. / Urol 177 369-376. 

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