Amino imbalance

Amino acids essential for young rats (98) and fishes (99) have been reviewed. Rats preferably eat a diet with sufficient amounts of essential amino acids rather than one that is deficient (100). Each essential amino acid, consumed in self-selection, has been reviewed (101). A protein diet with an excess of essential amino acids has been described as a poor protein diet from investigations that showed remarkable growth inhibition and occurrence of fatty fiver disease in rats (102). This is called amino acid imbalance (103). 

In the soil, an imbalance of amino acids, the presence of D-amino acids derived from microbial metabolism, or analogs and homologs of constituent protein amino acids could produce a deviation in the... 

An imbalance of amino acids in the blood often alters the rate of transport of these compounds into the brain, thereby affecting levels of neurotransmitters and rates of protein synthesis 670... 

Imbalances of brain amino acids may hinder the synthesis of brain lipids, leading to a diminution in the rate of myelin formation 671... 

Imbalances of brain amino acids may hinder the synthesis of brain lipids, leading to a diminution in the rate of myelin formation. Decreases of lipids, proteolipids and cerebrosides (Ch. 3) have been noted in several of these syndromes, e.g. maple syrup urine disease, when intra-myelinic edema is a prominent finding, particularly during the acute phase of metabolic decompensation [9]. Pathological changes in brain myelin are common, especially in infants who die early in life. The fundamental... 

Thus, it is possible that amino acids were first produced in a probiotic system. A slight enantiomeric imbalance in these amino acids might have been created by the action of some naturally occurring physical factors such as CPL. Alternatively, the imbalance might have been created in the presence of some physical factors at the time when these amino acids were formed. This imbalance might then have been amplified in other asymmetric reactions catalyzed by... 

Experimental results regarding the role of the histone tails indicate that these histone domains play a critical role in chromatin folding [358,365]. Removal as well as the modification (acetylation) of the lysine amino acids within these regions produces an imbalance of the electrostatic interactions, which results in a hierarchically impaired folding ability (H3/H4-H2A/H2B>H3/H4>H2A/H2B) of the chromatin fiber [358,366-369]. Therefore, sources of histone tail variability (histone variants and post-translational modifications other than lysine acetylation) are also likely to alter the extent of folding of chromatin. 

An imbalance of excitatory amino acids and of calcium homeostasis or both have been implied in the etiopathogenesis of a large number of neuropsychiatric illnesses including senile AD. Glutamate is an excitatory amino acid of the... 

Gupta M, Polinsky M, Senephansiri H, Snead OC, Jansen EEW, Jakobs C, Gibson KM (2004) Seizure evolution and amino acid imbalances in murine succinate semialdehyde dehydrogenase (SSADH) deficiency. Neurobiol Dis 16 556-562... 

Excesses of amino acids are not harmful—with few- exceptions. An imbalance of amino acids can result in a few instances. For example, a rat that feeds on eggwhite proteins with threonine orisoleucine added in high concentrations can experience an undesirable imbalance. 

Sergeeva, N.T. (1985). Effect of imbalance of fatty acid and amino acid composition of food on lipid metabolism in rainbow trout (In Russian). In Plastic Metabolism in Fish , pp.15-21, Kaliningrad. 

MCS is characterized by different phases and many different symptoms. Chronic fatigue is a symptom of MCS. It s also common for patients with fibromyalgia and CFS to be chemically sensitive. Chronic exhaustion along with MCS can have many causes small infections in the body, a yeast infection, sensitivity to electro smog, vitamin or mineral deficiency and, of course, chemical sensitivity. If the consistent avoidance of chemical substances does not bring about improvement, it s advisable to start researching other possible causes and to have yourself tested for a possible imbalance in vitamins, minerals and amino acids. 

We analyzed several organic and inorganic phases identified from the Murchison and Murray meteorites [100] in order to determine whether they contain any possible chirality besides the enantiomeric amino acids [98]. Asymmetric autocatalysis is a method capable of revealing chiral imbalances in various media, therefore, we employed this method as a possible chiral sensor for the meteorites. 

There is some imbalance in studying and describing those two phenomena. In spite of that, both of them were first predicted computationally [11, 12] only nonplanarity of amino- group had been confirmed experimentally [13] and attracted considerable attention in the literature (see, for example [14, 15]). In case of conformational flexibility of DNA bases, only indirect experimental evidences have been revealed [16-18], Therefore, in this review, we discuss in detail the current status of investigations on the ability of pyrimidine ring of DNA bases to fluctuate between planar and nonplanar states. 

Contraindications Tendency to fall asleep. Excessive use could cause dietary amino acid imbalance. 

Interestingly, even a 5% ee of alanine gave rise to the full ICD in 34 as induced by optically pure alanine (Fig. 17c), indicating a very strong majority rule (positive nonlinear) effect between the ee of amino acids and the observed ICD intensity [88]. This noticeable chiral amplification of 34 made it possible to detect an extremely small enantiomeric imbalance in the amino... 

In mammals, muscle breakdown or excess protein intake results in an imbalance between the fates of the carbon chains and the amino nitrogen. Unlike fat (lipid storage) or glycogen (carbohydrate storage), excess amino acids are not stored in polymeric form for later utilization. The carbon chains of amino acids are generally metabolized into tricarboxylic acid (TCA) cycle intermediates, although it is also possible to make ketone bodies such as acetoacetate from some. Conversion to TCA intermediates is easy to see in some instances. For example, alanine is directly transaminated to pyruvate. 

Radioactive amino acids are commonly used to follow protein synthesis. The procedure is in general similar to that used to follow synthesis of DNA, but in this case the cell s growth medium already contains high concentrations of amino acids and so the added radioactive amino acid acts as a tracer without causing imbalance. However, when it is desired to increase the extent of radioactive incorporation the presence of amino acids in the growth medium may be a disadvantage and their concentration may be reduced. Drastic reduction is obviously deleterious to cell growth ( 11.7] and preliminary experiments must be performed to ascertain what reduction can. be tolerated under the experimental conditions. 

Bernardini P, Fischer JE. Amino acid imbalance and hepatic encephalopathy. Annu Rev Nutr 2 419-454, 1982. 

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