Allergic-type reactions

The thiazide diuretics are contraindicated in patients with known hypersensitivity to the thiazides or related diuretics, electrolyte imbalances, renal decompensation, hepatic coma, or anuria. A cross-sensitivity reaction may occur with the thiazides and sulfonamides. Some of the thiazide diuretics contain tartrazine, which may cause allergic-type reactions or bronchial asthma in individuals sensitive to tartrazine. 

All monoclonal antibodies end in the suffix -mab. The syllable before -mab indicates the source of the monoclonal antibody (see Table 85-4). When administering an antibody for the first time, one should consider the source. The less humanized an antibody, the greater is the chance for the patient to have an allergic-type reaction to the antibody. The more humanized the antibody, the lower is the risk of a reaction. The severity of the reactions may range from fever and chills to life-threatening allergic reactions (which have resulted in death). Premedication with acetaminophen and diphenhydramine is common before the first dose of any antibody. If a severe reaction occurs, the infusion should be stopped and the patient treated with antihistamines, corticosteroids, or other supportive measures. 

The most frequent adverse effect associated with TIV is soreness at the injection site that lasts for less than 48 hours. TIV may cause fever and malaise in those who have not previously been exposed to the viral antigens in the vaccine. Allergic-type reactions (hives, systemic anaphylaxis) rarely occur after influenza vaccination and are likely a result of a reaction to residual egg protein in the vaccine. 

Alphoxalone Althesin Anaesthetic Allergic-type reaction 1972 U.K. 1984 12... 

Tartrazine/suifite sensitivity Some of these products contain tartrazine or sulfites, which may cause allergic-type reactions. 

Sulfite sensitivity Some of these products contain sulfites that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes. Sulfite sensitivity is seen more frequently in asthmatic or atopic nonasthmatic persons. 

Peripheral neuritis Peripheral neuritis evidenced by paresthesias, numbness, and tingling, has been observed. Add pyridoxine to the regimen if symptoms develop. Hematologic effects Blood dyscrasias consisting of reduction in hemoglobin and red cell count, leukopenia, agranulocytosis, and purpura have been reported. If such abnormalities develop, discontinue therapy. Periodic blood counts are advised. Tartrazine sensitivity Some of these products contain tartrazine, which may cause allergic-type reactions in susceptible individuals. Tartrazine sensitivity is frequently seen in patients who also have aspirin hypersensitivity. 

Hypersensitivity to diclofenac or to misoprostol or other prostaglandins. Do not give to patients who have experienced asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. 

Adverse reactions from 0.5% solution may include hyperemia pruritus discomfort tearing taste perversion use can lead to an allergic-type reaction. 

Allergic-type reaction may occur in those with tartrazine sensitivity. 

Allergic-type reactions, including anaphylaxis and life-threatening asthmatic exacerbation, may occur in patients with sulfite sensitivity. 

Because 2C-B is clandestinely produced, users are unaware of the dose they are ingesting and may be overwhelmed by the drug s effects. Users seeking MDMA-like effects do not expect or enjoy the unpleasant physical side effects on the body, including acute nausea, diarrhea, cramps, and gas. There are also several reports of allergic-type reactions causing increased mucus production concentrated in the windpipe and lungs. 

The literature is replete with reports of various allergic-type reactions to preservatives (parabens, chlorocresol), antioxidants (propyl gallate, metabisulphite), surfactants and solvents. The list is too long to be discussed in this article but Ref. contains a... 

Sulphites (metabisulphites) Can cause allergic-type reactions including anaphylactic S5unptoms and bronchospasm in susceptable people, especially those with a history of asthma or allergy... 

In preliminary trials, transient allergic-type reactions, that is urticaria, respiratory symptoms, and injection-site reactions, resulting from dose-dependent mast cell degranulation, were easily prevented by classical premedication (1). 

Anonymous. Possible allergic-type reactions. FDA Drug Bull 1987 17 2. 

America. The cffecliveness of bcnznida/olc is similar lo that of nifurtimox. Therapy tor American trypanosomiasis with oral bcnznidazolc requires several weeks and is t rcquenlly accompanied by adverse cfliecls such as peripheral neuropathy. bone marrow depression, and allergic-type reactions. 

The results of the extensive intake evaluations in the United States and in other countries demonstrated that intakes which were well below the acceptable daily intakes (ADIs) set by the Food and Drug Administration (FDA) and regulatory bodies in other countries, as well as the Joint FAO/WHO Expert Committee on Food Additives (JFECFA). The studies have also included evaluations of possible associations between aspartame and headaches, seizures, behavior, cognition, and mood as well as allergic-type reactions and use by potentially sensitive subpopulations, has continued after approval. Evaluation of the anecdotal reports of adverse health effects were the first ones done for a food additive, and revealed that the reported effects were generally mild and also common in the general population. 

In addition, rashes, conjunctivitis, and/or excessive perspiration were observed. These dermal and ocular reactions were not attributed to allergic-type reactions to the mercury. A 23-month-old boy who was exposed to an unspecified form of mercury also developed a "diffuse, pinpoint, erythematous, papular rash" and bright red fingertips "with large sheets of peeling skin" (Tunnessen et al. 1987). 

Porcine factor VIII, used in the treatment of patients with inhibitors to factor VIII, is not known to transmit human viruses. However, allergic-type reactions (e.g., fever, chills, skin rashes, nausea, and headaches) have been reported. Patients who experience these reactions may be treated with hydrocortisone and/or diphenhydramine. Thrombocytopenia is another potential complication of porcine factor VIII use. ... 

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