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Adverse drug reactions immediate

Monitoring and Managing Adverse Drug Reactions The nurse observes the patient at frequent intervals, especially during the first 48 hours of therapy. It is important to report to the primary health care provider the occurrence of any adverse reaction before the next dose of the drug is due The nurse should report serious adverse reactions, such as a severe hypersensitivity reaction, respiratory difficulty, severe diarrhea, or a decided drop in blood pressure, to the primary health care provider immediately because a serious adverse reaction may require emergency intervention. [Pg.88]

The nurse monitors vital signs every 4 hours or as ordered. Any adverse drug reactions or signs of toxicity are reported to the primary health care provider immediately. [Pg.261]

Educating the Patient and Family When Hie patient is hospitalized, the nurse explains all treatments and possible adverse effects to file patient before file initiation of therapy. The primary health care provider usually discusses the proposed treatment and possible adverse drug reactions with the patient and family members. The nurse briefly reviews these explanations immediately before parenteral administration of a drug. [Pg.599]

Both exocytotic and nonexocytotic mechanisms can contribute to adverse drug reactions that involve histamine release. Histamine is only one of several potent physiological mediators that are released from mast cells the other substances can also contribute to the overall immediate hypersensitivity reaction. [Pg.450]

If this complication occurs, the drug should be withdrawn immediately (7). A report has given some data on the frequency with which tiaprofenic acid cystitis-related disorders were reported to the UK s Committee on Safety of Medicines. Between 1981 and 1996, 770 adverse drug reactions involving 221 patients were reported. A peak in the reporting of cystitis was noted in 1994, when tiaprofenic acid product information was changed and advice was sent to UK doctors warning about cystitis-related... [Pg.3423]

The value of computational tools arises from their applicability early in development. An excellent correlation with wet laboratory data, an easy to use and interpretable model, high sensitivity, as well as high specificity are key requirements for a useful in silico model. As a nonexpert tool it should be available to the medicinal chemist via computer networks. Ideally such potentially powerful tools can be used to predict liabilities to induce an adverse drug reaction but also to guide the chemists to structurally modify the molecules via discovering the features that prevent the binding to the ion channel and immediately verify any successful chemical optimization step. [Pg.558]

URINAW ANTI-IN FECTIVES. The nurse observes tlie patient for adverse drug reactions. If an adverse reaction occurs, the nurse contacts tlie primary healtli care provider before the next dose of tlie drug is due However, serious drug reactions, such as a puhnonary reaction, are reported immediately. [Pg.463]

Chapter VI. clinical safety deals with the reporting of adverse drug reactions and events by the investigator to the sponsor, who shall report to the regulatory authority of the member state where the trial is in progress. The member state has the obligation to ensure that all serious adverse reactions and events are reported immediately to the EMEA. [Pg.342]

Educating the Patient and Family The nurse evaluates the patient s ability to assume responsibility for taking drug at home. The nurse explains any adverse reactions that may occur with a specific antianxiety drug and encourages die patient or family members to contact the primary health care provider immediately if a serious drug reaction occurs. [Pg.279]

MANAGING LACTIC ACIDOSIS. When taking metformin, the patient is at risk for lactic acidosis. The nurse monitors die patient for symptoms of lactic acidosis, which include unexplained hyperventilation, myalgia, malaise, gastrointestinal symptoms, or unusual somnolence If the patient experiences these symptoms, the nurse should contact the primary care provider at once. Elevated blood lactate levels of greater than 5 mmol/L are associated with lactic acidosis and should be reported immediately. Once a patient s diabetes is stabilized on metformin therapy, the adverse GI reactions that often occur at the beginning of such therapy are unlikely to be related to the drug therapy. A later occurrence of GI symptoms is more likely to be related to lactic acidosis or other serious disease. [Pg.507]

When iodine solutions are administered, the nurse observes Hie patient closely for symptoms of iodism and iodine allergy (see Adverse Reactions). If these occur, the nurse withholds tlie drug and immediately notifies the primary health care provider. This is especially important if swelling around or in the mouth or difficulty in breathing occurs. [Pg.536]

Educate the patient on common adverse drug effects and a few of the key signs and symptoms of severe toxicity (i.e., jaundice and abacavir hypersensitivity reaction). Tell them to call their provider immediately if any of those symptoms occur. Make sure they have the correct telephone number for the clinic. [Pg.1274]

Life-threatening adverse drug experience means any adverse drug experience that places the patient or subject, in the view of the investigator, at immediate risk of death from the reaction as it occurred, i.e., it does not include a reaction that, had it occurred in a more severe form, might have caused death. [Pg.82]

Adverse Reactions and Interactions of Drugs. Most protocols require that unexpected and severe, life-threatening, or fatal adverse experiences be reported immediately by telephone to the sponsor a 24-hour telephone number must be included in every protocol. The information provided on the drug reaction should be complete enough to enable the sponsor to provide the FDA with the proper and legal material necessary for reporting adverse experiences. [Pg.240]


See other pages where Adverse drug reactions immediate is mentioned: [Pg.194]    [Pg.195]    [Pg.217]    [Pg.232]    [Pg.233]    [Pg.250]    [Pg.166]    [Pg.777]    [Pg.1109]    [Pg.1182]    [Pg.243]    [Pg.2525]    [Pg.175]    [Pg.194]    [Pg.195]    [Pg.217]    [Pg.250]    [Pg.923]    [Pg.240]    [Pg.380]    [Pg.819]    [Pg.820]    [Pg.511]    [Pg.258]    [Pg.239]    [Pg.1912]    [Pg.990]   
See also in sourсe #XX -- [ Pg.283 ]




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Adverse drug reactions

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