Tiaprofenic acid, cystitis

If this complication occurs, the drug should be withdrawn immediately (7). A report has given some data on the frequency with which tiaprofenic acid cystitis-related disorders were reported to the UK s Committee on Safety of Medicines. Between 1981 and 1996, 770 adverse drug reactions involving 221 patients were reported. A peak in the reporting of cystitis was noted in 1994, when tiaprofenic acid product information was changed and advice was sent to UK doctors warning about cystitis-related... 

Theophylline, asthma, 17.2, 18.1, 18.2 Thiazides, see Diuretics Thiazolidinediones cardiovascular reactions, 31.697 musculoskeletal reactions, 32.779 peripheral edema, 29.531 Thiomersal, in vaccines, 28.357 Thiopurines, genetic susceptibility, 31.634 Thyroid hormones, 29.464 Thyroxine, drug interactions, 24.484 Tiaprofenic acid, cystitis, 18.106 TNF, see tumor necrosis factor Tolcapone, 32.289... 

Although many NSAIDs have rarely been reported to be responsible for increased urinary frequency and dysuria, and never for severe cystitis, tiaprofenic acid causes severe cystitis (SEDA-18, 106) (SEDA-20, 94) (SEDA-21, 107) (5,6). 

Crawford ML, Waller PC, Wood SM. Severe cystitis associated with tiaprofenic acid. Br J Urol 1997 79(4) 578-84. 

Brown EG, Waller PC, Sallie BA. Tiaprofenic acid and severe cystitis. Postgrad Med J 1998 74(873) 443-4. 

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