Management of adverse drug reactions

The expected outcomes for the patient depend on the reason for administration but may include an optimal response to therapy (infectious process controlled), management of adverse drug reactions, and an understanding of and compliance with the prescribed treatment regimen. 

Other environmental interactions Interference with diagnostic tests Diagnosis of adverse drug reactions Management of adverse drug reactions Monitoring therapy References... 

Sheffer AL, Pennoyer DS. Management of adverse drug reactions. J Allergy Clin Immunol 1984 74 580-8. 

Watkins J. Heuristic decision-making in diagnosis and management of adverse drug reactions in anaesthesia and surgery the case of muscle relaxants. Theor Surg 1989 4 212. 

OTHER ENVIRONMENTAL INTERACTIONS INTERFERENCE WITH DIAGNOSTIC TESTS DIAGNOSIS OF ADVERSE DRUG REACTIONS MANAGEMENT OF ADVERSE DRUG REACTIONS MONITORING THERAPY... 

Management of adverse drug reactions Preferential use of male donor plasma for FFP transfusions has led to a substantial reduction in the incidence of TRALI [6, 12 ]. Serious Hazards of Transfusion (SHOT) data suggest a 50% reduction in the risk of TRALI when 99% of FFP is from male donors only [33 ]. In another study, 12 of 21 allo-immune TRALI cases implicated plasma from female donors, suggesting that theoretically 57% of all allo-immune TRALI cases could be prevented by using male plasma only [14 ]. In another study there was no statistically significant difference in pulmonary morbidity between patients who received units from female or male donors, but these results were limited by the small number of morbid outcomes [11 ]. 

Management of adverse drug reactions Dexmedetomidine Combining dexmedeto-midine 5 micrograms/ml and morphine 1 mg/ml in intravenous patient-controlled analgesia resulted in better analgesia, reduced morphine consumption, and a reduced incidence of nausea and vomiting... 

Management of adverse drug reactions Side effects such as sedation, hypotension and seizures are correlated with clozapine serum levels, and monitoring is recommended with doses >600 mg per day or when there has been a change in concomitant pharmacotherapy or cigarette use [141 ]. 

Management of adverse drug reactions A case report of a 20-year-old patient receiving hemodialysis for CBZ overdose resulted in lowering of serum CBZ level from 20 mg/dL to 12.16 mg/dL over a 6-h span and resolution of patient s somnolence [61 ]. 

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