Advantages of increasing

Salmeterol is also available in a fixed ratio combination product containing fluticasone, and a new drug application has been filed for a fixed combination product containing budesonide and formoterol. Combination products have the potential advantage of increasing patient adherence due to the decreased number of inhalers and inhalations however, these products offer less flexibility with respect to dosage adjustments when necessary. 

Clearly L cannot be increased without limit, as the ohmic resistance of the electrodes will become sufficiently large to offset the advantages of increased areal capacity. While this problem has not been treated systematically, it is clear that the optimized value of L will be determined by the electronic... 

Bis-(2-methoxyethyl)aminosulfur trioxide (Deoxo-Fluor) has also been used in place of DAST. Deoxo-Fluor may have the advantage of increased thermal stability. A comparison of the two reagents for the cyclization of several peptidyl p-hydroxy amides has been reported (Table 8.13). 

GC-MS. This method has the advantage of increased sensitivity and selectivity. 

The advantageous properties of PNA-based biosensors represent an appealing alternative to DNA and aptamer based sensors under some circumstances. They offer advantages of increased sensitivity, selectivity, and stability, therefore they present valuable alternative to DNA/aptamer based sensors but have problems associated with solubility and synthetic procedure. 

Earlier it was pointed out that the use of ultramicroelectrodes could also give a several hundred times increase in iL compared with the diffusion-free currents at planar electrodes. The advantage of increasing the ability to measure at higher current densities by using short times in a transient technique with a planar electrode is that the magnitude of the currents is normal and is not forced down to the difficult-to-measure picoampere region that microelectrodes require. 

The need to measure concentrations in very small volumes is not restricted to biological systems. For example, open tubular columns for liquid chromatographic separations offer the advantage of increased resolution, but because their internal diameters may be as small as 15 pm, the amount of material in the eluted peaks is very small. Thus, the use of these columns requires detectors that can be used with low concentrations in small volumes. Jorgenson and co-workers showed that this could be accomplished by the insertion of a 10-pm-diameter, cylindrical electrode made from a carbon fiber into the end of the column [4]. The close fit between the column wall and the fiber ensured that a large fraction of the eluting molecules were electrolyzed. When the electrochemical data were collected in a voltammetric mode, the resolved compounds could be classi-... 

In a number of important industrial processes, it is necessary to carry out a reaction between a gas and a liquid. Usually the object is to make a particular product, for example, a chlorinated hydrocarbon such as chlorobenzene by the re action of gaseous chlorine with liquid benzene. Sometimes the liquid is simply the reaction medium, perhaps containing a catalyst, and all the reactants and products are gaseous. In other cases the main aim is to separate a constituent such as C02 from a gas mixture although pure water could be used to remove CO2, a solution of caustic soda, potassium carbonate or ethanolamine has the advantages of increasing both the absorption capacity of the liquid and the rate of absorption. The subject of gas-liquid reactor design thus really includes absorption with chemical reaction which is discussed in Volume 2, Chapter 12. 

Pyrolytic-laser-assisted CVD is analogous to thermally driven CVD, but instead of a diffuse heating source, a focused laser beam is used to define deposition areas spatially (32, 38, 39) or to heat the gas phase selectively (228). The use of laser has the added advantages of increased energy flux and rapid heating. To avoid photochemistry, the gas phase must be transparent to the radiation. 

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