Additional Cell Adhesion Proteins Are Required to Mediate the Immune Response

Additional Cell Adhesion Proteins Are Required to Mediate the Immune Response 

In addition to membrane-bound antibodies, TCR proteins and MHC proteins, other transmembrane proteins are required to obtain the specific cell-cell interactions necessary to mediate the immune response. These additional proteins 

Structures of class I and class II molecules as they would appear in the lipid bilayers of the cell membrane. Models show striking similarities between the two types of molecules. S—S indicates disulfide bridges in the class I and class II molecules and the j82 microglobulin. 

From this discussion we can see that a productive interaction between T cells and other cells requires a highly 

Left out of this discussion is an explanation for the source of the processed antigen on the antigen-presenting B cell. Immature B cells display a membrane-bound antibody, which interacts with circulating complementary antigen. Once bound to the antibody, the antigen is internalized, processed, and ultimately displayed by the MHC II protein on the cell surface of the same B cell. It is the interaction between such a B cell and the appropriate helper T cell that triggers the B cell to divide and differentiate. 

---

Additional Cell Adhesion Proteins Are Required to Mediate the Immune Response Immune Recognition Molecules Are Evolutionarily Related... 

---