Aconitum napellus

Rapid-acting channel-activating neurotoxin. It is obtained from the leaves and roots of various plants including wolfbane (Aconitum lycoctonum) and monkshood (Aconitum napellus). It is an off-white powder that is insoluble in water (0.03% ) but soluble in chloroform and benzene. Various salts have been reported. [Pg.468]

Ask the average person on the street about "natural products," and he or she is likely to mention the kinds of products found on the shelves of grocery stores and stores that specialize in "organic and "natural foods. Those items are overwhelmingly plant products, and they range from aconitum napellus (monkshood), alfalfa, allium cepa, aloe vera, angelica, and anise seed to witch hazel, yarrow, yellow dock, yohimhe hark, and yucca. [Pg.41]

SOURCE Roots of Aconitum napellus, A. Columbianum, A. ferox, and many others. Also present in seeds and, in small amounts, in all other parts of the plant. [Pg.80]

Aconitine. A poisonous drug from the dried tuberous root of Aconitum napellus. It was once given internally as a febrifuge and gastric anesthetic. [Pg.561]

Fico, G. et al., Flavonoids from Aconitum napellus subsp. Neomontanum, Phytochemistry, 57, 543, 2001. [Pg.124]

Glucosyl-7-(6"- -caffeoylglucosyl)(l — 3) rhamnoside Aconitum napellus ssp. neomontanum flowers Ranunculaceae 268... [Pg.769]

El-Sayed, N.H. et al., Kaempferol triosides from Reseda muricata. Phytochemistry, 57, 575, 2001. 261. Fico, G. et al.. New flavonol glycosides from the flowers of Aconitum napellus ssp. tauricum, Planta... [Pg.799]

Homeopathy Aconitum napellus, Belladonna, Bryonia, Chamomilla, Ferrum phosphoricum, Hepar sulphuris... [Pg.83]

Aconitum napellus L. China Aconitine, hypaconitine, mesaconitine, talaris amine.33 This herb is highly toxic. A cardiotonic. [Pg.178]

Datura innoxia, D. metel, D. stramonium, Hyoscyamus niger Datura innoxia, D. metel, D. stramonium, Hyoscyamus niger Aconitum napellus, A. carmichaelii Hypericum peiforatum... [Pg.520]

Another compound increasing the intracellular sodium concentration is the aconitine, a drug found in monkshood (Aconitum napellus) which is one of the most toxic plants in middle Europe. In cardiac muscle the alkaloid... [Pg.95]

Sources Aconitum napellus, Ranunculaceae LD50 (mice) 1 mg/kg (oral)... [Pg.99]

Highly toxic used to induce heart arrhythmia in experimental animals Aconitine. Alkaloid of Aconitum napellus... [Pg.739]

Songorine (Napellonine, Shimoburo Base I, Bulletine G) Aconitum napellus (fed on Aphids Brachycaudus aconitici)... [Pg.40]

Aconitum napellus L. ssp. castellanum J. Molero et C. Blanche 12-epi-O-Acetyl-1,19-dehydronapelline 12-epi-1,19Dehydronapelline Songoramine... [Pg.40]

Aconitum napellus L. S. Str. (syn. A. angli-cum Stapf.) Delphinium cardiopetalum DC2. [Pg.53]

Aconitum napellus L.S. Sir. (Syn. A. anglicum Stapf, A. napellus L. subsp. castellanum J. Molero et C. Blanche, A. nagarum var. lasiandrum W.T. Wang4 and A. karakolicum1 Rapaics, A. monticola3,5 Steinb. A. barbatiun Pers.7... [Pg.325]

Bulbs and corns are modified underground stems. They are collected when they are fully grown. Bulbs of Allium cepa and Allium sativa are used. Corm of Colchicum autumnale is the source of the drug. Dried seeds provide source of drugs such as Nux vomica and Ignatia. Lycopodium is produced from spores of the plant Lycopodium clavatum, Opium from the latex of the capsules of the poppy plant, Papaver somniferum and Carbo vegetabilis from the charcoal. Whole plants are also used for the preparation of drugs like Aconitum napellus, Calendula officinalis, Chamomilla, Phytolacca decandra (Cook, 1988). [Pg.3]

Aconites, commonly called wolfsbane or monkshood, are species of Aconitum (Ranunculaceae), valued ornamental herbaceous plants, grown for their showy blue or purple flowers, which are shaped like a monk s cowl. Their alkaloid content, mainly in the roots, makes them some of the most toxic plants commonly encountered. The dried roots of Aconitum napellus were once used, mainly externally for relief of pain, e.g. in rheumatism. The toxic alkaloids (0.3-1.5%) are complex diterpene-derived esters. Aconitine (Figure 6.124) is the principal component (about 30%) and is a diester of aconine with acetic and benzoic acids. Hydrolysis products benzoylaconine and aconine are also present in dried plant material. These alkaloids appear to behave as neurotoxins by acting on sodium channels. All species of Aconitum and Delphinium are potentially toxic to man and animals and must be treated with caution. [Pg.387]

Aconitum napellus (Aconite, monkshood, wolfsbane, soldier s cap)... [Pg.132]

Napelline (34) was isolated by Freudenberg and Roger (40) in 1937 from the poisonous roots of Aconitum napellus L. Recently, napelline has been isolated (41) from the tubers and roots of A. karakolicum, which were collected in the Terskei Ala-Tau ranges of the Kirghiz S.S.R. [Pg.112]

Aconitum napellus A. karakolicum Chemically correlated with songorine and lucidusculine Refs. 40-49... [Pg.203]

See also in sourсe #XX -- [ Pg.41 , Pg.183 ]

See also in sourсe #XX -- [ Pg.6 , Pg.165 , Pg.334 , Pg.357 , Pg.369 , Pg.440 , Pg.473 , Pg.489 , Pg.493 , Pg.495 , Pg.507 , Pg.511 , Pg.514 ]

See also in sourсe #XX -- [ Pg.3 ]

See also in sourсe #XX -- [ Pg.112 , Pg.203 ]

See also in sourсe #XX -- [ Pg.325 , Pg.327 ]

See also in sourсe #XX -- [ Pg.19 , Pg.20 ]

See also in sourсe #XX -- [ Pg.40 , Pg.95 ]

See also in sourсe #XX -- [ Pg.19 , Pg.20 ]

See also in sourсe #XX -- [ Pg.4 , Pg.17 , Pg.23 , Pg.81 , Pg.89 , Pg.92 , Pg.95 , Pg.96 ]

See also in sourсe #XX -- [ Pg.3 , Pg.4 , Pg.279 , Pg.295 , Pg.297 , Pg.343 ]

See also in sourсe #XX -- [ Pg.279 , Pg.295 , Pg.297 ]

See also in sourсe #XX -- [ Pg.22 ]

See also in sourсe #XX -- [ Pg.343 ]

See also in sourсe #XX -- [ Pg.41 , Pg.351 ]

See also in sourсe #XX -- [ Pg.566 ]

See also in sourсe #XX -- [ Pg.94 ]

See also in sourсe #XX -- [ Pg.7 , Pg.8 ]

See also in sourсe #XX -- [ Pg.33 ]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...