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Zoladex - Goserelin

Androgens have been considered to play a crucial role in the development and progression of prostate cancer, since men castrated before puberty do not develop prostate cancer (L10). Testosterone is the major steroid hormone that maintains prostate growth, function, and size. Treatment of stage D prostate cancer includes withdrawal of testosterone by surgical or medical castration, which causes atrophy of androgen-dependent cancer cells. Most treatments involve Zoladex (goserelin)... [Pg.107]

Fludara - fludarabine Panretin - alitretinoin Zoladex - goserelin... [Pg.395]

Zoladex (goserelin acetate injectable implant) Prostate cancer AstraZeneca... [Pg.230]

Zoladex Goserelin acetate Peptide hormone prostate/breast cancer... [Pg.69]

Zoladex Goserelin acetate PLGA Implant Prostate cancer M Shape... [Pg.198]

Zoladex Goserelin Peptide hormone prostate/breast... [Pg.54]

Goserelin (Zoladex), a hormonal antineoplastic drug used to treat breast cancer, is administered subcutaneously in an unusual way. The drag is contained in a dry pellet that is implanted in the soft tissue of the abdomen, where it is gradually absorbed during a period of 1 to 3 months. After a local anesthetic, such as lido-caine, is administered, a large needle (usually 16 gauge) is used to insert the pellet. [Pg.596]

Dutta AS, Furr BJA, Hutchinson FG. The discovery and development of goserelin (Zoladex). Pharma Med 1993 7 9-28. [Pg.79]

Flutamide (Eulexin) Fulvestrant (Faslodex) Goserelin (Zoladex) Leuprolide (Lupron, Lupron DEPOT, Lupron DEPOT-Ped, Eligard, Vantas)... [Pg.38]

Dosage forms Zoladex is supplied as a sterile, biodegradable implant containing goserelin acetate equivalent to 3.6mg of... [Pg.237]

Hormones Goserelin luteinizing hormone-releasing hormone (LHRH) deca peptide analogue Zoladex 1.3... [Pg.483]

Parenteral 100, 500 meg powder to reconstitute for subcutaneous or intravenous injection Goserelin (Zoladex)... [Pg.849]

Zoladex PLA Goserelin acetate Prostate cancer, endometreosis... [Pg.349]

Moghissi KS, Schlaff WD, Olive DL, Skinner MA, Yin H. Goserelin acetate (Zoladex) with or without hormone replacement therapy for the treatment of endometriosis. Fertil Steril 1998 69(6) 1056-62. [Pg.492]

Zinner NR, Bidair M, Ceneno A, Tomera K. Similar frequency of testosterone surge after repeat injections of goserelin (Zoladex) 3.6 mg and 10.8 mg results of a randomised open-label trial. Urology 2004 64 1177-81. [Pg.492]

Dosage Goserelin (GnRH Analog, Zoladex) Implants... [Pg.867]


See other pages where Zoladex - Goserelin is mentioned: [Pg.238]    [Pg.279]    [Pg.368]    [Pg.454]    [Pg.454]    [Pg.295]    [Pg.687]    [Pg.279]    [Pg.1895]    [Pg.215]    [Pg.238]    [Pg.279]    [Pg.368]    [Pg.454]    [Pg.454]    [Pg.295]    [Pg.687]    [Pg.279]    [Pg.1895]    [Pg.215]    [Pg.143]    [Pg.588]    [Pg.592]    [Pg.185]    [Pg.7]    [Pg.72]    [Pg.180]    [Pg.682]    [Pg.237]    [Pg.555]    [Pg.180]    [Pg.358]    [Pg.440]    [Pg.298]   


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Goserelin

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