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Injectable implant

Androgens come in oral, injectable, implantable, and topical preparations. Because of the toxicity of the oral preparations and the inconvenience of the injectable forms, the transdermal gels have been a major clinical advance for treatment of hypogonadal males. [Pg.732]

Fig. 42 Preparation of sterile injectable implants by extrusion of a mixture of OL-poly-lactide-glycolide and an active ingredient. Fig. 42 Preparation of sterile injectable implants by extrusion of a mixture of OL-poly-lactide-glycolide and an active ingredient.
Parenteral Administration Parenteral dosage forms include a wide variety of delivery routes, including injections, implants, and liposomes. The advantages of parenteral delivery systems is that they avoid first-pass effects, oral metabolism, and the harsh chemical environment of the stomach s gastric juices. The disadvantage is that the delivery mechanism is invasive. [Pg.69]

Table 1.7 Biodegradable implants for controlled sustained drug delivery Injectable implants Gels... Table 1.7 Biodegradable implants for controlled sustained drug delivery Injectable implants Gels...
Breeding colony management software that tracks projects, lines, matings and litters, injections, implantations, pedigrees, phenotypes, and genotypes... [Pg.372]

Poly-L-Lactic acid is a physical adjunct that is an injectable implant of microparticles of poly-L-lactic acid. It is indicated in restoration and/or correction of signs of facial fat loss (lipoatrophy) in people with HIV. [Pg.577]

Eliaz RE, Kost J. Characterization of polymeric PLGA-injectable implant delivery system for the controlled release of proteins. J Biomed Matter Res 2000 50 388-396. [Pg.270]

Zoladex (goserelin acetate injectable implant) Prostate cancer AstraZeneca... [Pg.230]

Chandrashekar, G. and Udupa, N., 1996. Biodegradable injectable implant systems for long term drug delivery using poly(lactic-co-glycolic) acid copolymers. J. Pharm. Pharmacol, 48(7), 669-674. [Pg.128]

Radomsky, M.L. et al., 1993. The controlled release of Ganirelix from the Atrigel injectable implant system. Proc. Intern. Symp. Control. Rel. Bioact. Mater., 20. [Pg.137]

Shah, N.H. et al, 1993. A biodegradable injectable implant for delivering micro and macromolecules using poly(lactic-co-glycolic) acid (PLGA) copolymers. Journal of... [Pg.138]

Shah, N. H., Railkar, A. S., Chen, F. C., Tarantino, R., Kumar, S., Muijani, M., Palmer, D., Infeld, M. H. Malick, A. W. (1993) A biodegradable injectable implant for dehvering micro and macromolecules using poly (lactic-co-glycohc) acid (PLGA) copolymers. Journal of Controlled Release, 21, 139-47. [Pg.178]

Jordan O, Doelker E, Rufenacht DA. Biomaterials used in injectable implants (liquid embolics) for percutaneous filling of vascular spaces. Cardiovasc Intervent Radiol 2005 28(5) 561-569. [Pg.372]

Title Injectable Implants for Tissue Augmentation And Generation... [Pg.464]

Inventors D.W. Urry, P. Glazer, and T.M. Parker Title Injectable Implants for Tissue Augmentation And Generation ... [Pg.464]

An impurity level as low as 5ppb may also be inadequate when the biomaterial is used as a rapidly dispersible injectable implant. Five parts per billion is the detection limit of the highly sensitive immunoblot technique. Fortunately, adequate purification of protein-based polymers used at 30 mg quantities has been achieved at BRL, and adequate purification has been demonstrated for the most stringent of conditions, where an injectable implant totally disperses having unloaded all of its impurities in a few days time. To have passed such a stringent test provides the desired gold standard for purification. Now it will be useful to increase the sensitivity of impurity detection by means of radiolabeling and to establish quality control for the level of purity required when... [Pg.489]

When active substances are encapsulated in drug delivery systems, their bioavailability and therapeutic index can be improved over an extended period of time. A drug delivery system including polymer microspheres has been developed for injection, implants, transdermal patches, and aerosols (34). [Pg.240]

Delivery of Proteins from a Controlled Release Injectable Implant... [Pg.93]

Dunn, R. L., Yewey, G. L., and Tipton, A. J., 1992, An injectable implant delivery system for tissue growth factors, American Association of Pharmaceutical Scientists Western Regional Meeting, Las Vegas. [Pg.116]


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See also in sourсe #XX -- [ Pg.54 , Pg.55 ]




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Injectable implant drug delivery system

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