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Goserelin acetate

There are no comparative trials of LHRH agonists, so the choice is usually based on cost (Table 65-1) and on patient and physician preference. Leuprolide acetate is administered daily. Leuprolide depot and goserelin acetate implant can be administered monthly, or every 12 or 16 weeks. [Pg.729]

Gonadotropin-releasing hormone (GnRH) analogs buserelin acetate goserelin acetate leuprolide acetate nafarelin acetate... [Pg.606]

Dosage forms Zoladex is supplied as a sterile, biodegradable implant containing goserelin acetate equivalent to 3.6mg of... [Pg.237]

Zoladex PLA Goserelin acetate Prostate cancer, endometreosis... [Pg.349]

A 47-year-old woman developed symptoms of thyrotoxicosis (palpitation, tremor, tachycardia, and goiter) due to Graves disease, after using goserelin acetate for 13 months (30). [Pg.488]

One of 66 women randomized to receive goserelin acetate for uterine fibroids withdrew from the study owing to severe pelvic pain (78). [Pg.490]

Moghissi KS, Schlaff WD, Olive DL, Skinner MA, Yin H. Goserelin acetate (Zoladex) with or without hormone replacement therapy for the treatment of endometriosis. Fertil Steril 1998 69(6) 1056-62. [Pg.492]

Morita S, Ueda Y. Graves disease associated with goserelin acetate. Acta Med Nagasaki 2002 47 79-80. [Pg.492]

Goserelin acetate is available in the form of implantable cylinders, 1-1.5 mm in diameter, that are placed subcutaneously in the upper abdominal area. Goserelin is metabolized in the liver and excreted in the urine. Clearance is greater in women than in men. Stimulation of gonadotropins occurs in the first weeks of therapy, followed by suppression. [Pg.867]

Goserelin acetate 3.6 mg SC monthly Transient flare of tumor symptoms, pain at injection site Hot flushes, impotence, gynecomastia... [Pg.1303]

Antibiotics bacitracin, bleomycin, gramicidine, capreomycin Hormones corticotropin, glucagon, gonadrolein HC1, leuprolide acetate, histrelin acetate, oxytocin, secretin, goserelin acetate, vassopressin... [Pg.36]

In contrast to these microsphere formulations, Zoladex (AstraZeneca) is a small implantable cylinder (approximately 1mm in diameter and 10 mm in length) containing goserelin acetate in a polymer matrix of 50 50 PLG. This system delivers approximately 3.6 mg drug over a 1-month period and is indicated for the treatment of prostate cancer. A second Zoladex system containing 10.6 mg goserelin has also been developed to release the drug for over 3 months. ... [Pg.178]

Denis LJ, Camelro de Moura JL, Bono A, et al. Goserelin acetate and flutamide versus bilateral orchiectomy A phase 111 EORTC trial (30853). EORTC GU Group and EORTC Data Center. Urology 1993 42 119-129. [Pg.2437]

The Norplant device has been somewhat controversial, however, due to difficulties associated with its removal. A second example of an implantable drug delivery system is Zoladex, which is an implantable biodegradable lactide/glycolide polymeric delivery system for the administration of goserelin acetate. It is available in one-month and three-month presentations and can be injected through a wide-bore needle. [Pg.346]

Gonadorelin acetate Gonadorelin HCl Nafarelin acetate Leuprolide acetate Buserelin Goserelin acetate... [Pg.529]

See other pages where Goserelin acetate is mentioned: [Pg.452]    [Pg.143]    [Pg.588]    [Pg.1365]    [Pg.345]    [Pg.573]    [Pg.620]    [Pg.237]    [Pg.237]    [Pg.279]    [Pg.452]    [Pg.298]    [Pg.879]    [Pg.589]    [Pg.483]    [Pg.405]    [Pg.2320]    [Pg.454]    [Pg.735]    [Pg.1747]    [Pg.2430]    [Pg.279]    [Pg.311]   
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See also in sourсe #XX -- [ Pg.573 ]

See also in sourсe #XX -- [ Pg.394 ]

See also in sourсe #XX -- [ Pg.346 ]

See also in sourсe #XX -- [ Pg.311 ]

See also in sourсe #XX -- [ Pg.298 ]

See also in sourсe #XX -- [ Pg.7 ]



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Goserelin

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