Biodegradable implants

R., Chasin, M., Tamargo, R., and Colvin, O, M., The intracerebral delivery of BCNU with surgically implanted biodegradable polymers A quantitative autoradiographic study, Proc. [Pg.69]

As for non-degradable polymeric implants, biodegradable polymeric implants are divided into two main... [Pg.89]

Kimura H.-O.Y., Hashizoe, M., Nishiwaki, H., Honda, Y. and Ikada, Y. (1994) A new vitreal drug delivery system using an implantable biodegradable polymeric device. Investigative Ophthalmology and Visual Science, 35 2815-2819. [Pg.318]

Peri D, Bogdansky S, Allababidi S, Shah JC. Development of an implantable, biodegradable, controlled drug delivery system for local antibiotic therapy. Drug Dev Ind Pharm 1994 20 1341-1352. [Pg.310]

Grossman SA, Reinhard C, Colvin OM, et al. The intracerebral distribution of BCNU delivered by surgically implanted biodegradable polymers. J Neurosurg 1992 76 640-647. [Pg.21]

Zoladex (gosorelin acetate implant) biodegradable polymeric particles capable of continuously delivering gosorelin for 3 months as a palliative treatment for advanced prostate cancer. [Pg.368]

The Norplant device has been somewhat controversial, however, due to difficulties associated with its removal. A second example of an implantable drug delivery system is Zoladex, which is an implantable biodegradable lactide/glycolide polymeric delivery system for the administration of goserelin acetate. It is available in one-month and three-month presentations and can be injected through a wide-bore needle. [Pg.346]

Hashizoe M, Ogura Y, Takanashi T, Kunou N, Honda Y, Ikada Y. Implantable biodegradable polymeric device in the treatment of experimental proliferative vitreoretinopathy. Curr Eye Res 1995 14 473-477. [Pg.190]

Williams JA, Dillehay LE, Tabassi K, Sipos E, Fahlman C, Brem H. Implantable biodegradable polymers for lUdR radiosensitization of experimental human malignant glioma. J Neurooncol 1997 32 181-192. [Pg.380]

Foda, N.H., El-Iaithy, M. and Tadros, I. (2007) Implantable biodegradable sponges effect of interpolymer complex formation of chitosan with gelatin on the release behavior of tramadol hydrochloride. Drug Development and Industrial Pharmacy, 33(1), 7-17. [Pg.86]

Eventually, an implantable, biodegradable medical device can be formed from a homogeneous polymer blend. The fabrication proceeds in detail as follows (12) ... [Pg.228]

In regenerative medicine, there are various different materials suitable as implantable scaffolds. These can be fabricated from natural or synthetic materials. Common examples are polysaccharides (eg, chitosan), or polyesters (eg, poly e-caprolactone), for natural and synthetic polymers, respectively. However, they are both capable of degradation (either enzyme mediated, or hydrolysis) in vivo (Bassi et al., 2011 Cunha-Reis et al., 2007). Often, polyesters are used as implantable biodegradable biomaterials, as they have controllable degradation and mechanical properties through formation of block copolymers. Where degradation occurs, the scaffolds... [Pg.389]

Goosen, M., Leung, Y., Chou, S., and Sun, A., 1982, Tnsiilin-alhumin microbeads An implantable, biodegradable system. Biomater. Med Devices Artif Organs 10 205 218. [Pg.86]

Dexametha- sone Ozurdex Intravitreal implant Biodegradable PLGA Renal vonous congestion In production... [Pg.337]

Brimonidine Intravitreal implant Biodegradable PLGA Age-related macular degeneration Phase 2... [Pg.337]

Triam- cinolone acetonide RETAAC Intravitreal implant Biodegradable PLGA Diabetie macnlar edema Phasel... [Pg.337]

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