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Lupron DEPOT

Appendix C contains a list of the NDAs within the scope of the study. The drug products included in the study represent some of the largest dmg products as measured by annual sales, including so-called blockbuster drugs such as Capoten, Cardizem CD, Cipro, Claritin, Lupron Depot, Neurontin, Paxil, Pepcid, Pravachol,... [Pg.26]

Flutamide (Eulexin) Fulvestrant (Faslodex) Goserelin (Zoladex) Leuprolide (Lupron, Lupron DEPOT, Lupron DEPOT-Ped, Eligard, Vantas)... [Pg.38]

I Brand Name(s) Eligard, Lupron, Lupron Depot, Lupron Depot-Gyn, Lupron Depot-Ped, Viadur... [Pg.682]

Injection Depot Formulation-. 3.75 (Lupron Depot), 7.5 mg (Eligard, Lupron Depot, Lupron Depot-Ped), 11.25 ( Lupron Depot, Lupron Depot-Ped, Lupron Depot-Gyn), 15 mg (Lupron Depot-Ped), 22.5 mg (Eligard, Lupron Depot), 30 mg (Lupron Depot). [Pg.682]

Advanced prostatic carcinoma IM (Lupron Depot) 7.5 mg every month or 22.5 mg q3moor30mgq4mo. Subcutaneous(Eligard) 7.5mgeverymonthor22.5 mgq3mo or30mgq4mo. Subcutaneous (Lupron) 1 mg/day. Subcutaneous (Viadur) 65 mg implanted ql2mo. [Pg.683]

Eligard 7.5 mg is contraindicated in patients with hypersensitivity to GnRH, GnRH agonist analogs or any of the components 30 mg Lupron Depot and the implant form are contraindicated in women... [Pg.683]

B. Indications and use Lupron Injection, Lupron Depot, Lupron Depot-3 Month, and Lupron Depot-4 Month are indicated in the palliative treatment of advanced prostate cancer. These products offer an alternative treatment when orchiectomy or estrogen administration is either not indicated or unacceptable to the patient. Lupron Injection Pediatric and Lupron Depot-PED are indicated in the treatment of children with central precocious puberty. Lupron Depot and Lupron Depot-3 Month are indicated for the management of endometriosis, including pain relief and reduction of endometriotic lesions. [Pg.234]

Route of administration Lupron Injection is intended for subcutaneous injection. Lupron Depot is intended for intramuscular injection. [Pg.235]

Recommended dosage and monitoring requirements According to Micromedex, the effective doses of Lupron in prostate cancer are 1 mg subcutaneously daily, or in the depot formulation 7.5 mg intramuscularly (IM) monthly, 11.25 mg every 3 months, or 30 mg every 4 months. Lupron Depot-3 month 22.5 mg is used in the treatment of advanced prostate cancer. In endometriosis, the effective dose is 3.75mg depot IM monthly or 11.25mg every 3 months for 6 months. In central precocious puberty, the recommended starting dose of Lupron Injection Pediatric is 50pg/kg... [Pg.235]

Lupron-3 Month SR Depot 22.5 mg [SY] Lupron Depot-4 Month 30 mg [SY]... [Pg.516]

Lupron Depot PLA Leuprolide acetate Prostate cancer, endometreosis... [Pg.349]

Parenteral depot suspension (Lupron Depot, Depot-Ped, Depot-3, Depot-4) lyophilized microspheres to reconstitute for IM injection (3.75, 7.5, 11.25, 15, 22.5, 30 mg/vial)... [Pg.879]

Based on these limitations, only a limited number of drug delivery systems based on biodegradable polymers have so far been successfully commercialized. One example is Lupron Depot one-month injectable microspheres of PLGA containing leuprorelin acetate (LH-RH agonist) for the treatment of endometriosis and prostatic cancer [31,32]. [Pg.70]

The Lupron Depot comprises a PLA/PLGA microsphere delivery system for the delivery of the GnRH analog, leuprolide, over a 1-, 3-, or 4-month period. The release rate is determined by the polymer composition and molecular weight (Table 4.5). [Pg.92]

The Lupron Depot microspheres are indicated for the treatment of male patients with prostate cancer and female patients suffering from endometriosis and anemia due to fibroids. Each depot formulation is... [Pg.92]

Which of the following products is made of a surface-eroding polymer (a) Lupron Depot (b) Zoladex (c) Gliadel and/or (d) Vitrasert. [Pg.103]

See other pages where Lupron DEPOT is mentioned: [Pg.580]    [Pg.143]    [Pg.231]    [Pg.81]    [Pg.538]    [Pg.100]    [Pg.203]    [Pg.683]    [Pg.235]    [Pg.236]    [Pg.458]    [Pg.484]    [Pg.516]    [Pg.516]    [Pg.516]    [Pg.516]    [Pg.21]    [Pg.279]    [Pg.203]    [Pg.580]    [Pg.269]    [Pg.83]    [Pg.483]    [Pg.92]    [Pg.93]   
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See also in sourсe #XX -- [ Pg.203 ]

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See also in sourсe #XX -- [ Pg.177 , Pg.2320 ]

See also in sourсe #XX -- [ Pg.203 ]

See also in sourсe #XX -- [ Pg.113 ]

See also in sourсe #XX -- [ Pg.279 ]



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