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GnRH Analogs

B. H. Vickery and B. Luneneld, GnRH Analogs in Cancer and Human Reproduction, Kluwer Academic, Lancaster, UK, 1989. [Pg.125]

Anti androgens GnRH analogs Steroid synthesis inhibitors f>a reductase inhibitors Testosterone receptor inhibitors... [Pg.24]

Palomba S, Falbo A, Russo T, Zullo F (2006a) GnRH analogs use for the treatment of symptomatic leiomyomas. Gynecol Surg 2 7-13... [Pg.319]

Leuprolide (Lupron, Lupron DEPOT, Lupron DEPOT-Ped, EMgard, Vantas) [Antineoplastic/GnRH Analog] Uses ... [Pg.203]

Chemical Class Gonadotropin-releasing hormone (GnRH) analog I Clinical Pharmacology ... [Pg.682]

Other GnRH analogs Goserelin, histreiin, nafareiin, and triptorelin ... [Pg.847]

Ironically, sustained non-pulsatile administration of GnRH or GnRH analogs inhibits the release of FSH and LH by the pituitary in both women and men, resulting in hypogonadism. [Pg.864]

GnRH binds to receptors on pituitary gonadotrophs. Pulsatile intravenous administration of GnRH every 1-4 hours stimulates FSH and LH secretion. As noted above, GnRH administered continuously or GnRH analogs administered in depot formulations inhibit gonadotropin release. [Pg.864]

GnRH analog therapy for the purpose of producing pituitary suppression leads to a transient rise in sex hormone concentration during the first 2 weeks of treatment. This can be deleterious during treatment of prostate cancer, precocious puberty, and infertility. [Pg.865]

Dosage Nafarelin (GnRH Analog, Synarel) Nasal Solution... [Pg.866]

Dosage Goserelin (GnRH Analog, Zoladex) Implants... [Pg.867]

GnRH analog (leuprolide, nafarelin) treatment of children is generally well tolerated. However, temporary exacerbation of precocious puberty may occur during the first few weeks of therapy. Injection site reactions occur in about 5%. Nafarelin nasal spray may cause or aggravate sinusitis. [Pg.868]

The Lupron Depot comprises a PLA/PLGA microsphere delivery system for the delivery of the GnRH analog, leuprolide, over a 1-, 3-, or 4-month period. The release rate is determined by the polymer composition and molecular weight (Table 4.5). [Pg.92]


See other pages where GnRH Analogs is mentioned: [Pg.558]    [Pg.310]    [Pg.310]    [Pg.315]    [Pg.380]    [Pg.15]    [Pg.343]    [Pg.837]    [Pg.837]    [Pg.839]    [Pg.840]    [Pg.840]    [Pg.847]    [Pg.920]    [Pg.923]    [Pg.440]    [Pg.864]    [Pg.865]    [Pg.866]    [Pg.867]    [Pg.868]    [Pg.868]    [Pg.973]    [Pg.974]    [Pg.99]    [Pg.280]    [Pg.289]    [Pg.289]    [Pg.289]    [Pg.290]    [Pg.136]    [Pg.137]    [Pg.812]   


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GnRH

GnRH Analogs with Agonist Activity

GnRH agonists/analogs

Gonadotropin-releasing hormone GnRH) analogs

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