Wound healing delivery systems

JA Hubbell. Hydrogel systems for barriers and local drug delivery in the control of wound healing. I Controlled Release 39 305-313, 1996. 

While uncontrolled topical delivery of proteins and peptides for local application such as open wound healing is easily achieved, it is much more challenging to use transdermal delivery systems to deliver protein across intact skin. In theory, transdermal delivery could provide constant drug release for days, avoids first-pass metabolism, and could allow drug effects to be rapidly terminated by simply removing... 

Spanning the most recent technologies in the field, this source covers current methods, clinical applications, and new delivery systems to treat and prevent proliferative eye disease...examines the factors that trigger and perpetuate intraocular wound healing in diseases such as proliferative vitreoretinopathy...reviews the results of clinical trials of new sustained delivery implants...and analyzes the potential of intraocular drug delivery for the treatment of posterior segment diseases. 

The effects of silver-coated materials on healing have been studied by numerous researchers. It has been discovered that the sustained delivery of silver ions from silver nanoparticles reduces systemic inflammation of burn, promotes wound healing and reduces infection. For example, silver has been used to reduce catheter-assodated urinary tract infections. In addition. 

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