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To exhaustively screen a library to be sure to include a (statistically) certain change from one specific amino acid in a certain position to another specific one in the same position, a library size of 1 /p3 = (1 /8.8 x 10-11) = 1.14 x 1010 is required Given the possible library sizes of up to 1015 or less (see Section 11.3 below), only the distance of one or two amino acids can be covered with certainty. In other words, variants that require more than one or two amino acid changes, or variants that require cooperative changes in amino acid sequence, stand a low chance of being detected quickly, even with a perfect assay. [Pg.313]

The word may be a variant spelling. See Spelling, above, and look up other possible forms. [Pg.553]

While there are mairy variants of the basic, model, one can show that there is a well-defined minimal set of niles that define a lattice-gas system whose macroscopic behavior reproduces that predicted by the Navier-Stokes equations exactly. In other words, there is critical threshold of rule size and type that must be met before the continuum fluid l)cliavior is matched, and onec that threshold is reached the efficacy of the rule-set is no loner appreciably altered by additional rules respecting the required conservation laws and symmetries. [Pg.16]

This first case vividly illustrates the importance of the boundary condition. Indeed, Poisson s equation or the system of field equations have an infinite number of solutions corresponding to different distributions of masses located outside the volume. Certainly, we can mentally picture unlimited variants of mass distribution and expect an infinite number of different fields within the volume V. In other words, Poisson s equation, or more precisely, the given density inside the volume V, allows us to find the potential due to these masses, while the boundary condition (1.83) is equivalent to knowledge of masses situated outside this volume. It is clear that if masses are absent in the volume V, the potential C7 is a harmonic function and it is uniquely defined by Dirichlet s condition. [Pg.29]

I turn the page. The next is in a much older hand, though fluent enough in its still-Gothic style, the spelling more variant, the words and their ordering more foreign to the eye. [Pg.382]

Published also in the same year under titles A chain of philosophical reflexions and, Philosophical reflexions and inquiries. A variant edition first word of title measures 56 mm. Other editions from same year have first word of title measuring 73 mm. [Pg.32]

Research into the risk factors for Cluster A personality disorders has focused on genetic factors. In particular, many researchers have looked for a shared genetic linkage between these disorders and schizophrenia. Only schizotypal personality appears to be genetically linked to schizophrenia. It may be that STPD exists on a biological continuum with schizophrenia. In other words, STPD could theoretically be a far milder variant of Axis I schizophrenia. There is less evidence linking PPD or SPD to schizophrenia nevertheless, certain characteristic symptoms of these other disorders also overlap with schizophrenia. [Pg.318]

Swartz and Stenzel (1984) proposed an approach to widen the applicability of the cathode initiation of the nucleophilic substitution, by using a catalyst to facilitate one-electron transfer. Thus, in the presence of PhCN, the cathode-initiated reaction between PhBr and Bu4NSPh leads to diphe-nydisulfide in such a manner that the yield increases from 10 to 70%. Benzonitrile captures an electron and diffuses into the pool where it meets bromobenzene. The latter is converted into the anion-radical. The next reaction consists of the generation of the phenyl radical, with the elimination of the bromide ion. Since generation of the phenyl radical takes place far from the electrode, this radical is attacked with the anion of thiophenol faster than it is reduced to the phenyl anion. As a result, instead of debromination, substitution develops in its chain variant. In other words, the problem is to choose a catalyst such that it would be reduced more easily than a substrate. Of course, the catalyst anion-radical should not decay spontaneously in a solution. [Pg.276]

The previous sections discussed the advection-dispersion equation and variants such as the mobile-immobile conceptualization, which are based on the key assumption that mechanical dispersion is Fickian. In other words, the advection-dispersion equation (Eq. 10.5) is strictly valid only under perfectly homogeneous... [Pg.225]

Special terminology based on trade names has been employed for some polymers. Although trade names should be avoided, one must be familiar with those that are firmly established and commonly used. An example of trade-name nomenclature is the use of the name nylon for the polyamides from unsubstituted, nonbranched aliphatic monomers. Two numbers are added onto the word nylon with the first number indicating the number of methylene groups in the diamine portion of the polyamide and the second number the number of carbon atoms in the diacyl portion. Thus poly(hexamethylene adipamide) and polyfhexamethylene sebacamide) are nylon 6,6 and nylon 6,10, respectively. Variants of these names are frequently employed. The literature contains such variations of nylon 6,6 as nylon 66, 66 nylon, nylon 6/6, 6,6 nylon, and 6-6 nylon. Polyamides from single monomers are denoted by a single number to denote the number of carbon atoms in the repeating unit. Poly(e-caprolactam) or poly(6-aminocaproic acid) is nylon 6. [Pg.16]

Should development come after speciation Yes, of course, in the new model it is natural, one produces the Anlage and develops it to its potential. The word evolution is derived from the latin term evolvere which means to roll out and that describes precisely the process postulated in the Genomic Potential Hypothesis for the post-Cambrian time. With speciation behind us there remain two distinct ph ases of evolution in the widest sense of the word, the streamlining of the chemistry in the nucleus, which leaves no traces other than species-specific stem cells, and the post-Cambrian unrolling of species and variants that produces a spectacular display of phenotypes. Looks like we are on the right track. [Pg.51]

Cornforth et al.54 introduced a variant of the Cram model to be used when one of the substituents is highly electronegative (halogens, etc.). The electronegative group X is oriented anti to the oxygen, to minimize dipolar interactions. In other words, X plays the role of the bulky substituent. [Pg.166]


See other pages where Words word variants is mentioned: [Pg.13]    [Pg.462]    [Pg.126]    [Pg.549]    [Pg.193]    [Pg.116]    [Pg.176]    [Pg.396]    [Pg.161]    [Pg.851]    [Pg.416]    [Pg.79]    [Pg.77]    [Pg.16]    [Pg.192]    [Pg.52]    [Pg.115]    [Pg.71]    [Pg.78]    [Pg.462]    [Pg.193]    [Pg.67]    [Pg.30]    [Pg.111]    [Pg.178]    [Pg.59]    [Pg.100]    [Pg.222]    [Pg.193]    [Pg.223]    [Pg.316]    [Pg.184]    [Pg.157]    [Pg.236]    [Pg.4]    [Pg.90]   
See also in sourсe #XX -- [ Pg.57 ]

See also in sourсe #XX -- [ Pg.57 ]




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